Browse our anti-Crystallin, alpha A (CRYAA) Antibodies

Full name:: anti-Crystallin, alpha A Antibodies (CRYAA)

On www.antibodies-online.com are 134 Crystallin, alpha A (CRYAA) Antibodies from 20 different suppliers available. Additionally we are shipping Crystallin, alpha A Proteins (66) and Crystallin, alpha A Kits (13) and many more products for this protein. A total of 213 Crystallin, alpha A products are currently listed.

Synonyms:: Acry-1, AI323437, alpha-a-crystallin, Crya-1, Crya1, CRYAA, cryaa-A, CTRCT9, DAcry-1, HspB4, lop18, wu:fc06h04, zgc:92036

list all antibodies	Gene Name	GeneID	UniProt
	CRYAA	1409	P02489
	CRYAA	12954	P24622
	CRYAA	24273	P24623
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Most Popular Reactivities for anti-Crystallin, alpha A (CRYAA) Antibodies

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anti-Human Antibodies:

anti-Mouse (Murine) Antibodies:

70 WB Antibodies

anti-Rat (Rattus) Antibodies:

74 WB Antibodies

All available anti-Crystallin, alpha A Antibodies

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Relevant Pathways for anti-Crystallin, alpha A Antibodies

M Phase

More product categories related to Crystallin, alpha A Antibody

Top referenced anti-Crystallin, alpha A Antibodies

Human Polyclonal CRYAA Primary Antibody for WB - ABIN1881229 : Deng, Chen, Xie, Zhao, Gong, Liu, Zhang, Sun, Liu, Ma, Batra, Li: The small heat shock protein alphaA-crystallin is expressed in pancreas and acts as a negative regulator of carcinogenesis. in Biochimica et biophysica acta 2010 (PubMed)
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More Antibodies against Crystallin, alpha A Interaction Partners

Human Crystallin, alpha A (CRYAA) interaction partners

our results suggest that glutathione and ascorbate, as the major anti-oxidant compounds within lenticular tissues, demonstrate controversial effect on structure and chaperone-like activity of human alphaA-Cry (show CRY2 Antibodies).
Alternative mRNA splicing of human alpha A-crystallin leads to an additional, formerly not characterized alpha A-crystallin species which is able to modulate the properties of the canonical ensemble of alpha-crystallin oligomers.
a silent single nucleotide polymorphism [D2D] (CRYAA: C to T transition) mutation results in a compact CRYAA mRNA secondary structure, while the wild type CRYAA mRNA has a weak or loose secondary structure
Low crystallin alpha a expression is associated with pancreatic tumorigenesis.
The results suggest that the N-terminal domain of CRYAA is required during in vitro complex formation with filensin (show BFSP1 Antibodies) and phakinin (show BFSP2 Antibodies).
CRYAA polymorphism is a genetic marker of inter-individual differences in the risk of nuclear ARC (show NOL3 Antibodies).
Results demonstrated that CRYAA rs7278468 and CRYAB (show CRYAB Antibodies) rs370803064/rs387907338 are correlated with the risk and clinicopathological features of children suffering from congenital cataract.
These mutations revealed a range of detrimental effects on the structure, stability and functional properties of aA-Cry (show CRY2 Antibodies) which all together can explain the pathomechanisms underlying development of the associated congenital cataract disorders
CRISPR/Cas9-mediated mutation of the alphaA-crystallin gene in rabbits recapitulates phenotypes of congenital cataracts, microphthalmia, obscurity, and early atrophy of the lens, and failed differentiation of lens fibers.
The study demonstrates that residues 70-88 in CRYAA act as a primary substrate binding site and account for the bulk of the total chaperone activity.

Mouse (Murine) Crystallin, alpha A (CRYAA) interaction partners

findings offer additional insight into the early transcriptional changes caused by Cryaa and Cryab (show CRYAB Antibodies) mutations associated with autosomal dominant cataracts, and indicate that the transcript levels of certain genes are affected by the expression of mutant alpha-crystallin in vivo
Collectively, these studies show that FGF signaling up-regulates expression of alphaA-crystallin both directly and indirectly via up-regulation of c-Maf (show MAF Antibodies).
Knockout of alphaA-crystallin inhibited pathologic neovascularization through the VEGF (show VEGFA Antibodies) and VEGFR2 (show KDR Antibodies) signaling pathways both in vitro and in vivo.
p53 (show TP53 Antibodies) can regulate lens differentiation by controlling expression of the differentiation genes coding for the lens crystallins.
Alpha A crystallin is a moonlighting protein that functions as a heat shock protein as well as a lens crystalline.
alphaA-crystallin may protect against geographic atrophy.
alphaA and alphaB regulate caspase-3 (show CASP3 Antibodies) and Bax (show BAX Antibodies) in vitro and in vivo to regulate lens differentiation.
these findings show that mutation of alphaA-crystallin induces activation of the UPR during cataract formation.
Hydroimidazolone modification of human alphaA-crystallin: Effect on the chaperone function and protein refolding ability.
Methionine oxidation of alpha-crystallin in combination with loss of MsrA (show MSR1 Antibodies) repair causes loss of alpha-crystallin chaperone function.

Rabbit Crystallin, alpha A (CRYAA) interaction partners

Cow (Bovine) Crystallin, alpha A (CRYAA) interaction partners

For moderate O-GlcNAcylation on bovine crystalline alpha, the preferred amino acids were Pro > Ala > Gly at position -2, Ala > Thr (show TRH Antibodies) >Val > Lys (show LYZ Antibodies) > Pro at position -1, and Ala > Gly > Arg > Glu (show DCTN1 Antibodies) at position +2.
Alpha-crystallin, in the presence of the sorbitol dehydrogenase (SDH (show SORD Antibodies)) pyridine cofactor NAD(H), can exert a remarkable chaperone action by favoring the recovery of the enzyme activity from chemically denaturated SDH (show SDS Antibodies) up to 77%.
Conserved triad in alphaA-crystallin contributes to stability of higher order oligomers but is not essential for formation of tetramers.
Mass spectrometry analysis and a database search identified carbamylated proteins originating from alphaA-crystallin, betaB2- and gammaS-(betaS)-crystallins.

Xenopus laevis Crystallin, alpha A (CRYAA) interaction partners

The ontogeny and localization of the alphaA-crystallin and betaB1-crystallin (show CRYBB1 Antibodies) during embryonic lens development and regeneration indicated a different development program, although they have identical origins, the ectoderm.

Zebrafish Crystallin, alpha A (CRYAA) interaction partners

The normal development observed in alphaA-crystallin deficient zebrafish embryos may reflect similarly non-essential roles for this protein in the early stages of both zebrafish and mammalian lens development.
Fndings establish that the C-terminal extension of alphaA crystallin can be either 3D domain swapped or non-3D domain swapped.
alphaA-crystallin (HSPB4) is expressed during development.

Crystallin, alpha A (CRYAA) Antigen Profile

Antigen Summary

Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. {ECO:0000269|PubMed:22120592}.

Alternative names and synonyms associated with Crystallin, alpha A (CRYAA)

crystallin alpha A (CRYAA) antibody
crystallin, alpha A (Cryaa) antibody
alphaA-crystallin (CpipJ_CPIJ005646) antibody
crystallin, alpha A (CRYAA) antibody
crystallin alpha A (cryaa) antibody
crystallin alpha A (Cryaa) antibody
alpha-crystallin A chain-like (LOC100384978) antibody
crystallin alpha A S homeolog (cryaa.S) antibody
alpha-crystallin A chain (LOC458589) antibody
crystallin, alpha A (cryaa) antibody
alpha-crystallin A chain (LOC102724652) antibody

Acry-1 antibody
AI323437 antibody
alpha-a-crystallin antibody
Crya-1 antibody
Crya1 antibody
CRYAA antibody
cryaa-A antibody
CTRCT9 antibody
DAcry-1 antibody
HspB4 antibody
lop18 antibody
wu:fc06h04 antibody
zgc:92036 antibody

Protein level used designations for CRYAA

alpha-crystallin A chain , crystallin, alpha-1 , heat shock protein beta-4 , human alphaA-crystallin (CRYA1) , crystallin, alpha 1 , lens opacity 18 , alphaA-crystallin , alpha A crystallin , alpha-A-crystallin , alpha-A-crystallin protein , alpha-crystallin A chain-like , Crystallin, alpha polypeptide A , crystallin, alpha A , [a]A-crystallin , hspb4 , Alpha-crystallin A chain , Heat shock protein beta-4

GENE ID	SPECIES
1409	Homo sapiens
12954	Mus musculus
418546	Gallus gallus
487786	Canis lupus familiaris
497275	Ovis aries
6037267	Culex quinquefasciatus
100009294	Oryctolagus cuniculus
100049490	Oryzias latipes
100135506	Cavia porcellus
100384978	Callithrix jacchus
100460863	Pongo abelii
24273	Rattus norvegicus
281718	Bos taurus
378668	Xenopus laevis
458589	Pan troglodytes
722370	Macaca mulatta
791110	Ornithorhynchus anatinus
100000769	Danio rerio
100051134	Equus caballus
101083874	Felis catus
101520527	Ochotona princeps
101828899	Mesocricetus auratus
102724652	Homo sapiens

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Show all anti-Crystallin, alpha A (CRYAA) Antibodies with Pubmed References