anti-MAP2K2 Antibodies
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anti-MAP2K2 antibody (Mitogen-Activated Protein Kinase Kinase 2) (AA 1-50) Primary Antibody
1
anti-MAP2K2 antibody (Mitogen-Activated Protein Kinase Kinase 2) (AA 262-292) Primary Antibody
anti-MAP2K2 antibody (Mitogen-Activated Protein Kinase Kinase 2) (AA 1-30) Primary Antibody
5
anti-MAP2K2 antibody (Mitogen-Activated Protein Kinase Kinase 2) (AA 200-229) Primary Antibody
5
anti-MAP2K2 antibody (Mitogen-Activated Protein Kinase Kinase 2) (AA 1-400) Primary Antibody
anti-MAP2K2 antibody (Mitogen-Activated Protein Kinase Kinase 2) (AA 1-360) Primary Antibody
anti-MAP2K2 antibody (Mitogen-Activated Protein Kinase Kinase 2) Primary Antibody
anti-MAP2K2 antibody (Mitogen-Activated Protein Kinase Kinase 2) (Center) Primary Antibody
anti-MAP2K2 antibody (Mitogen-Activated Protein Kinase Kinase 2) (Center) Primary Antibody
anti-MAP2K2 antibody (Mitogen-Activated Protein Kinase Kinase 2) (pThr394) Primary Antibody
MAP2K2 Antigen Profile
Protein Summary
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.
Alternative names and synonyms associated with MAP2K2
- mitogen-activated protein kinase kinase 2 (MAP2K2) antibody
- mitogen-activated protein kinase kinase 2 (Map2k2) antibody
- mitogen activated protein kinase kinase 2 (Map2k2) antibody
- MAP kinase kinase 2 (MKK2) antibody
- mitogen-activated protein kinase kinase 2b (map2k2b) antibody
- AA589381 antibody
- ATMKK2 antibody
- CFC4 antibody
- F27B13.50 antibody
- F27B13_50 antibody
- MAP KINASE KINASE 1 antibody
- MAP kinase kinase 2 antibody
- MAPKK2 antibody
- MEK2 antibody
- MK1 antibody
- MK2 antibody
- MKK2 antibody
- Prkmk2 antibody
- zgc:172250 antibody
Protein level used designations for MAP2K2
ERK activator kinase 2 , MAP kinase kinase 2 , MAPK/ERK kinase 2 , dual specificity mitogen-activated protein kinase kinase 2 , mitogen-activated protein kinase kinase 2, p45 , MAP kinase/Erk kinase , MAPKK 2 , MEK 2 , mitogen activated protein kinase kinase 2 , protein kinase, mitogen activated, kinase 2, p45 , MEK2 , mitogen-activated protein kinase kinase type 2 , dual specificity mitogen activated protein kinase kinase 2
| GENE ID | SPECIES |
|---|---|
| 5605 | Homo sapiens |
| 26396 | Mus musculus |
| 58960 | Rattus norvegicus |
| 396349 | Gallus gallus |
| 611939 | Canis lupus familiaris |
| 510434 | Bos taurus |
| 829103 | Arabidopsis thaliana |
| 100728923 | Cavia porcellus |
| 100002225 | Danio rerio |
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- anti-Mitogen-Activated Protein Kinase Kinase Kinase 13 Antibodies
- anti-Mitogen-Activated Protein Kinase Kinase Kinase 14 Antibodies
- anti-Mitogen-Activated Protein Kinase Kinase Kinase 15 Antibodies
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- anti-Mitogen-Activated Protein Kinase Kinase Kinase 8 Antibodies
- anti-Mitogen-Activated Protein Kinase Kinase Kinase 9 Antibodies
