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anti-Human MAPK13 Antibodies:
anti-Mouse (Murine) MAPK13 Antibodies:
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Human Monoclonal MAPK13 Primary Antibody for IF, WB - ABIN968270
Jiang, Zhang, Chen, Zhou, Liu, Bian, Zhou, Chen: [Study on the needle biopsies of 100 prostatic adenocarcinoma]. in Zhonghua bing li xue za zhi Chinese journal of pathology 2002
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AtMKK6 (show MAP2K6 Antibodies)-AtMPK13 (show MAPK1/3 Antibodies) module positively regulates lateral root formation.[AtMPK13 (show MAPK1/3 Antibodies)]
The p38delta (show MAPK1/3 Antibodies) mitogen-activated protein kinase (show MAPK1 Antibodies) was identified as a novel regulator of NLRP3 (show NLRP3 Antibodies) inflammasome activation in primary human macrophages, and thus, represents a potential target for modulation of atherosclerotic inflammation.
p38delta (show MAPK1/3 Antibodies) expression was significantly higher in esophageal squamous cell carcinoma tissues compared with paired normal controls. No significant association was found for p38delta (show MAPK1/3 Antibodies) between its expression and other clinicopathological parameters. In Eca109 cells, p38delta (show MAPK1/3 Antibodies) can promote the cell growth and motility. p38delta (show MAPK1/3 Antibodies) overexpression promotes tumorigenesis in nude mice when p38delta (show MAPK1/3 Antibodies) was stably over-expressed and p38ga...
MAPK13 gene knockdown using siRNA reduced the aldehyde dehydrogenase high cell population and abrogated the tumor-initiating ability.
p38gamma (show MAPK12 Antibodies) and p38delta (show MAPK1/3 Antibodies) reprogram liver metabolism by modulating neutrophil infiltration and provide a potential target for NAFLD (show TSC2 Antibodies) therapy
MAPK13 (show MAPK1/3 Antibodies) undergoes a larger interlobe configurational rearrangement upon activation compared with MAPK14 (show MAPK14 Antibodies).
PKCdelta (show PKCd Antibodies) activates a MEKK1 (show MAP3K1 Antibodies)/MEK3 (show MAP2K3 Antibodies)/p38delta (show MAPK1/3 Antibodies) MAPK (show MAPK1 Antibodies) cascade to increase p53 (show TP53 Antibodies) levels and p53 (show TP53 Antibodies) drives p21(Cip1 (show CDKN1A Antibodies)) gene expression.
esophageal squamous cell carcinoma cell lines which are p38delta (show MAPK1/3 Antibodies)-negative grew more quickly than cell lines which express endogenous p38delta (show MAPK1/3 Antibodies).
DNA methylation (show HELLS Antibodies) alterations are widespread in melanoma; epigenetic silencing of MAPK13 (show MAPK1/3 Antibodies) contributes to melanoma progression
Data indicate that p38delta (show MAPK1/3 Antibodies) mediates oncogene (show RAB1A Antibodies)-induced senescence through a p53 (show TP53 Antibodies)- and p16(INK4A (show CDKN2A Antibodies))-independent mechanism.
GSK3alpha, GSK3beta (show GSK3b Antibodies), and MAPK13 (show MAPK1/3 Antibodies) were found to be the most active tau kinases, phosphorylating tau at all four epitopes.
Results reveal that p38delta (show MAPK1/3 Antibodies) contributes both cell-autonomous and paracrine effects during the course of skin tumor formation.
p38gamma (show MAPK12 Antibodies) and p38delta (show MAPK1/3 Antibodies) control heart growth by modulating mTOR (show FRAP1 Antibodies) pathway through DEPTOR (show DEPTOR Antibodies) phosphorylation and subsequent degradation.
Together, our results establish that p38gamma (show MAPK12 Antibodies) and p38delta (show MAPK1/3 Antibodies) are central to colitis-associated colon cancer formation through regulation of hematopoietic cell response to injury, and validate p38gamma (show MAPK12 Antibodies) and p38kappa as potential targets for cancer therapy.
p38gamma (show MAPK12 Antibodies) and p38delta (show MAPK1/3 Antibodies) are crucial regulators of inflammatory joint destruction in collagen-induced arthritis.
p27 (show CDKN1B Antibodies) inhibition of COX-2 (show COX2 Antibodies) expression was specifically due to phosphorylation of transcription factor cAMP response element binding (CREB (show CREB1 Antibodies)) phosphorylation mediated by p38beta (show MAPK11 Antibodies) and p38delta (show MAPK1/3 Antibodies).
Aberrant p38delta (show MAPK1/3 Antibodies)-PKD1 (show PKD1 Antibodies) signaling in neutrophils may underlie development of acute lung injury and life-threatening acute respiratory distress syndrome.
p38gamma (show MAPK12 Antibodies) and p38delta (show MAPK1/3 Antibodies) kinases regulate the Toll-like receptor 4 (TLR4 (show TLR4 Antibodies))-induced cytokine production by controlling ERK1/2 (show MAPK1/3 Antibodies) protein kinase (show CDK7 Antibodies) pathway activation
results indicate that p38gamma (show MAPK12 Antibodies) and p38delta (show MAPK1/3 Antibodies) have a role in the suppression of tumor development
This gene encodes a member of the mitogen-activated protein (MAP) kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The encoded protein is a p38 MAP kinase and is activated by proinflammatory cytokines and cellular stress. Substrates of the encoded protein include the transcription factor ATF2 and the microtubule dynamics regulator stathmin. Alternatively spliced transcript variants have been observed for this gene.
MAP kinase 13
, MAPK 13
, MAP kinase p38 delta
, mitogen-activated protein kinase p38 delta
, stress-activated protein kinase 4
, SAPK/Erk/kinase 4
, mitogen activated protein kinase 13
, p38 delta MAP kinase
, mitogen-activated protein kinase 13