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This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS).
MAP kinase-activated protein kinase 1b
, MAPK-activated protein kinase 1b
, MAPKAP kinase 1b
, insulin-stimulated protein kinase 1
, p90-RSK 3
, ribosomal S6 kinase 2
, ribosomal protein S6 kinase alpha-3
, 90 kDa ribosomal protein S6 kinase 3
, ribosomal protein S6 kinase 2
, ribosomal protein S6 kinase polypeptide 3
, ribosomal protein S6 kinase, 90kDa, polypeptide 3