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Based on the results, an MTRA2756G polymorphism which changes activity and stability of the methionine synthase associated with prostate cancer in men.
MTR CpG sites were hypermethylated in preterm placenta. Methylated CpG sites were negatively associated with maternal plasma vitamin B12 (show NDUFB3 Proteins) levels.
tagSNPs in MTHFR (show MTHFR Proteins), MTR, MTRR (show MTRR Proteins), and TCN2 (show TCN2 Proteins) were not associated with NSCLP in our study, but continued exploration, including allele frequency of various populations and molecular mechanism of the gene-gene interactions of the genes, may provide additional insight into NSCLP.
MTHFR (show MTHFR Proteins) A1298C and MS A2756G polymorphisms may be unrelated to male infertility.
The evaluation of genetic association showed that, MTHFR (show MTHFR Proteins) C6877T (OR: 8.89, 95% CI: 2.01-39.40) and MTR A2756G (OR: 1.48, 95% CI: 1.09-2.00) polymorphisms associated with higher risk of CVD.
The MTR A2756G, MTRR (show MTRR Proteins) A66G, MTHFR (show MTHFR Proteins) C677T and MTHFR (show MTHFR Proteins) A1298C polymorphisms were assessed. MTR A2756G, MTRR (show MTRR Proteins) A66G, and MTHFR (show MTHFR Proteins) C677T gene polymorphisms were associated with the risk of NSCL (show NHLH1 Proteins)/P (all p < 0.05). Logistic regression analysis revealed that MTR A2756G, MTR RA66G, and MTHFR (show MTHFR Proteins) C667T might increase the risk of Nonsyndromic Cleft Lip/Palate
we examined the association between methylenetetrahydrofolate reductase (MTHFR (show MTHFR Proteins) C677T, rs1801133) and methionine synthase (MTR A2756G, rs1805087) polymorphisms and risk for thyroid and breast cancer. We found an association between MTHFR (show MTHFR Proteins) C677T polymorphism and risks to both thyroid (OR = 2.50; 95%CI = 1.15-5.46; P = 0.02) and breast cancer (OR = 2.53; 95%CI = 1.08-5.93; P = 0.03).
the studied polymorphisms MTHFR (show MTHFR Proteins) C677T (rs1801133) and MTR A2756G (rs1805087) do not contribute to genetic susceptibility to varicose veins in ethnical Russians.
Data suggest that the MTR-A2756G polymorphism is associated with male infertility risk.
MTR A2756G single nucleotide polymorphism is significantly associated with gastric cancer risk in Korea.
These findings indicate that greater synthesis of phosphatidylcholine (show SGMS1 Proteins) and antioxidants contribute to the better performance and immuno-metabolic status in methionine-supplemented cows.
MTR encodes the enzyme 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G.
5-methyltetrahydrofolate-homocysteine methyltransferase 1
, cobalamin-dependent methionine synthase
, methionine synthase
, vitamin-B12 dependent methionine synthase
, 5-methyltetrahydrofolate--homocysteine methyltransferase