Browse our anti-TUBB2B (TUBB2B) Antibodies

Full name:: anti-Tubulin, beta 2B Antibodies (TUBB2B)

On www.antibodies-online.com are 59 Tubulin, beta 2B (TUBB2B) Antibodies from 15 different suppliers available. Additionally we are shipping TUBB2B Proteins (6) and many more products for this protein. A total of 69 TUBB2B products are currently listed.

Synonyms:: 2410129E14Rik, bA506K6.1, fb40f09, N-Tub, n-tubulin, NBT, NST, ntubulin, PMGYSA, RGD1309427, TUBB, TUBB2, TUBB2A, TUBB2B, tubb2c, wu:fb40f09, Xn-tubulin, zgc:123194

list all antibodies	Gene Name	GeneID	UniProt
	TUBB2B	73710	Q9CWF2
	TUBB2B	291081	Q3KRE8
	TUBB2B	347733	Q9BVA1
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Most Popular Reactivities for anti-TUBB2B (TUBB2B) Antibodies

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anti-Mouse (Murine) TUBB2B Antibodies:

4 WB Antibodies

anti-Rat (Rattus) TUBB2B Antibodies:

2 WB Antibodies

anti-Human TUBB2B Antibodies:

All available anti-TUBB2B Antibodies

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Relevant Pathways for anti-TUBB2B Antibodies

Microtubule Dynamics

More product categories related to TUBB2B Antibody

Top referenced anti-TUBB2B Antibodies

Human Polyclonal TUBB2B Primary Antibody for WB - ABIN531677 : Madeddu, Farace, Tolu, Solinas, Asara, Sotgiu, Delogu, Prados, Sotgiu, Montella: Cytoskeletal proteins in the cerebrospinal fluid as biomarker of multiple sclerosis. in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2013 (PubMed)

More Antibodies against TUBB2B Interaction Partners

Cow (Bovine) Tubulin, beta 2B (TUBB2B) interaction partners

A combination of molecular dynamics simulations and computational docking is used to identify a single high-affinity binding site on five beta-tubulin (show TUBB Antibodies) microtubule inhibitors adjacent to the exchangeable GTP (show AK3 Antibodies) site on beta-tubulin (show TUBB Antibodies).
Results suggest that the axonemal motif sequences of betaI, betaIV and betaV tubulin (show TUBB Antibodies) are essential for ciliary function.
These data indicate that phosphorylation of tubulin (show TUBB Antibodies) by Cdk1 (show CDK1 Antibodies) could be involved in the regulation of microtubule dynamics during mitosis.

Mouse (Murine) Tubulin, beta 2B (TUBB2B) interaction partners

The data presented here demonstrate that a heterozygous Tubb2b brdp/+ mutation in mice leads to significant spatial learning and memory reductions and conditioned contextual, but not cued, fear deficits.
study shows TUBB2B significantly upregulated in melanoma multinucleated giant cells, which indicates that it may play an important role in melanoma metastasis.
Study showed that Tubb2b is expressed in Sox2 (show SOX2 Antibodies)- and Tbr2 (show EOMES Antibodies)-positive neuronal progenitors and, at higher levels, in Dcx (show DCX Antibodies)-positive postmitotic neurons in the developing mouse neocortex
Results show that the missense mutation at a highly conserved residue (N247S) in Tubb2b gene represents the most severely affected mouse tubulin (show TUBB Antibodies) phenotype involving neuronal proliferation and survival.

Human Tubulin, beta 2B (TUBB2B) interaction partners

The TUBB2B mutation described here represents an unusual recessive mode of inheritance for missense-mediated tubulinopathies and reinforces the sensitivity of the developing cerebellum to microtubule defects.
At the cellular level, the p.Cys239Phe TUBB2B mutant leads to tubulin (show TUBB Antibodies) heterodimerization impairment, decreased ability to incorporate into the cytoskeleton, microtubule dynamics alteration, with an accelerated rate of depolymerization
off-target, non-immune mediated effects of the mTOR (show FRAP1 Antibodies)-inhibitor everolimus on the podocyte cytoskeleton might involve regulation of microtubules, revealing a potential novel role of TUBB2B and DCDC2 (show DCDC2 Antibodies) in glomerular podocyte development
The association of polymicrogyria with thin or absent corpus callosum, dysmorphic basal ganglia, brainstem and vermis hypoplasia is highly likely to result from mutations in TUBB2B.
The present study confirms that mutations in tubulin (show TUBB Antibodies) genes are responsible for complex brain malformation.
Congenital fibrosis of the extraocular muscles and intellectual disability segregate with a heterozygous mutation in TUBB2B.
The TUBB2B and TUBA1 (show TUBA4A Antibodies) coding regions have been sequenced in patients with cortical malformations associated with these genes.
Three new TUBB2B mutations have been identified in three unrelated patients with a diffuse and rather symmetrical cortical abnormality.
Brain malformations are associated with mutations in the beta-tubulin (show TUBB Antibodies) gene TUBB2B, supporting its critical role in migration/organization and axon guidance processes.
TUBB2B is required for neuronal migration two disease-associated mutations lead to impaired formation of tubulin (show TUBB Antibodies) heterodimers.

TUBB2B Antigen Profile

Antigen Summary

The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. This gene is highly similar to TUBB2A and TUBB2C. Defects in this gene are a cause of asymmetric polymicrogyria.

Alternative names and synonyms associated with TUBB2B

tubulin, beta 2B class IIb (TUBB2B) antibody
tubulin, beta 2B class IIB (Tubb2b) antibody
tubulin, beta 2B class IIb (Tubb2b) antibody
tubulin beta 2B class IIb (TUBB2B) antibody
tubulin beta 2B class IIb (tubb2b) antibody
hypothetical protein (MW1385) antibody
tubulin beta 2B class IIb S homeolog (tubb2b.S) antibody
tubulin, beta 2b (tubb2b) antibody
tubulin beta-2A chain (LOC101122734) antibody

2410129E14Rik antibody
bA506K6.1 antibody
fb40f09 antibody
N-Tub antibody
n-tubulin antibody
NBT antibody
NST antibody
ntubulin antibody
PMGYSA antibody
RGD1309427 antibody
TUBB antibody
TUBB2 antibody
TUBB2A antibody
TUBB2B antibody
tubb2c antibody
wu:fb40f09 antibody
Xn-tubulin antibody
zgc:123194 antibody

Protein level used designations for TUBB2B

, , , , , , , , , , , , , , , , , , tubulin beta-2B chain tubulin, beta 2A class IIa tubulin, beta polypeptide beta-tubulin T beta15 (aa 1-445) t beta-15 tubulin, beta 2 class II beta-tubulin isotype class IIb beta-tubulin tubulin, beta polypeptide paralog neural beta-tubulin tubb-paralog beta-tubulin class-II tubulin beta-2 chain tubulin, beta 2B hypothetical protein beta-2-tubulin tubulin, beta, 2 tubulin beta-2A chain tubulin, beta 2B class IIb

GENE ID	SPECIES
281555	Bos taurus
73710	Mus musculus
291081	Rattus norvegicus
347733	Homo sapiens
394889	Xenopus (Silurana) tropicalis
420883	Gallus gallus
462400	Pan troglodytes
478702	Canis lupus familiaris
1003497	Staphylococcus aureus subsp. aureus MW2
100021036	Monodelphis domestica
379220	Xenopus laevis
641421	Danio rerio
101122734	Ovis aries musimon

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