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anti-Human TUBG1 Antibodies:
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All Species Monoclonal TUBG1 Primary Antibody for ICC, WB - ABIN302067
Haren, Remy, Bazin, Callebaut, Wright, Merdes: NEDD1-dependent recruitment of the gamma-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly. in The Journal of cell biology 2006
Show all 13 Pubmed References
Human Monoclonal TUBG1 Primary Antibody for ICC, WB - ABIN94313
Libusová, Sulimenko, Sulimenko, Hozák, Dráber: gamma-Tubulin in Leishmania: cell cycle-dependent changes in subcellular localization and heterogeneity of its isoforms. in Experimental cell research 2004
Show all 14 Pubmed References
Human Polyclonal TUBG1 Primary Antibody for WB - ABIN1881959
Alvarado-Kristensson, Rodríguez, Silió, Valpuesta, Carrera: SADB phosphorylation of gamma-tubulin regulates centrosome duplication. in Nature cell biology 2009
Show all 3 Pubmed References
Chicken Polyclonal TUBG1 Primary Antibody for ICC, IF - ABIN265871
Heckler, Zeleke, Divekar, Fernandez, Tiek, Woodrick, Farzanegan, Roy, Üren, Mueller, Riggins: Antimitotic activity of DY131 and the estrogen-related receptor beta 2 (ERRβ2) splice variant in breast cancer. in Oncotarget 2016
Human Polyclonal TUBG1 Primary Antibody for IF, IHC (p) - ABIN4620380
Solc, Baran, Mayer, Bohmova, Panenkova-Havlova, Saskova, Schultz, Motlik: Aurora kinase A drives MTOC biogenesis but does not trigger resumption of meiosis in mouse oocytes matured in vivo. in Biology of reproduction 2012
MPK6 (show MAPK6 Antibodies) phosphorylates EB1c, but not EB1a, and has a role in maintaining regular planes of cell division under stress conditions.
Authors report that the only viral nonstructural protein able to reproduce the loss of gamma-tubulin from the microtubule organizing center and the loss of integrity of the microtubule system is Foot-and-mouth disease virus 3C(pro).
that in the face of predominant gamma-tubulin-1 expression, the accumulation of gamma-tubulin-2 (show TUBG2 Antibodies) in mature neurons and neuroblastoma (show ARHGEF16 Antibodies) cells during oxidative stress may denote a prosurvival role of gamma-tubulin-2 (show TUBG2 Antibodies) in neurons
All GCPs are incorporated into the helix via lateral interactions between their N-terminal domains, whereas the C-terminal domains mediate longitudinal interactions with gamma-tubulin.
While binding to gamma-tubulin may help target APC (show APC Antibodies) to the site of microtubule nucleation complexes, additional C-terminal sequences of APC (show APC Antibodies) are required to stimulate and stabilize microtubule growth.
a causative link between altered function of AURKA-HMMR-TPX2-TUBG1 and breast carcinogenesis in BRCA1/2 mutation carriers
Results show that CUL4A (show CUL4A Antibodies)- and CUL4B (show CUL4B Antibodies)-mediated polyubiquitination of gamma-tubulin for its degradation.
In this study, the molecular basis of interaction between two lateral gamma-tubulin units within the gamma-tubulin ring complex were elucidated by making extensive use of molecular mechanics and molecular dynamics techniques.
Gamma tubulin expression was associated with patients' age, astrocytoma grade, respectability, patient survival and performance. These factors may be important prognostic indicators for patients with astrocytomas.
Recombinant gamma-tubulin can be phosphorylated by Cdk1 (show CDK1 Antibodies)-cyclin B or Brsk1 (show BRSK1 Antibodies) and dephosphorylated by Ppp4c (show PPP4C Antibodies)-R2-R3A in vitro.
Nek9 (show NEK9 Antibodies) phosphorylates NEDD1 (show NEDD1 Antibodies) on Ser377 driving its recruitment and thereby that of gamma-tubulin to the centrosome in mitotic cells.
Our results reveal for the first time an increased expression of TUBG1 and TUBG2 (show TUBG2 Antibodies) in lung cancer
Fodrin is a regulatory transporter of gamma-tubulin to the centrosomes for normal progression of mitosis.
Data suggest that localization of Tubg1 (and Plk1 (show PLK1 Antibodies) [polo-like kinase 1 (show PLK1 Antibodies)]) to spindle poles during oocyte meiotic maturation/oogenesis (metaphase I/II) requires participation of Uchl5ip/Haus7 (HAUS augmin-like complex subunit 7 (show HAUS7 Antibodies)).
a direct interaction with NEDD1 (show NEDD1 Antibodies) regulates gamma-tubulin recruitment to the centrosome
Gamma-tubulin is a key regulator of asymmetric cytokinesis in mouse oocytes.
pPKCdelta(Thr505) interacts with MTOC-associated proteins pericentrin (show PCNT Antibodies) and gamma-tubulin, and plays a role in meiotic spindle organization in oocytes
Results suggest that Fyn (show FYN Antibodies) and PI3K might take part in the modulation of membrane-associated gamma-tubulin activities.
SADB (show BRSK1 Antibodies) kinase activity controls centrosome homeostasis by regulating phosphorylation of gamma-tubulin.
Data show that depletion of either gamma-tubulin or XMAP215 (show CKAP5 Antibodies) was partially rescued by adding back XMAP215 (show CKAP5 Antibodies), but not by adding any of the other factors.
This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7.
Tubulin gamma-3 chain
, tubulin gamma-1 chain
, gamma-tubulin complex component 1
, tubulin, gamma polypeptide
, gamma tubulin