Browse our anti-Solute Carrier Family 27 (Fatty Acid Transporter), Member 4 (SLC27A4) Antibodies

Human Solute Carrier Family 27 (Fatty Acid Transporter), Member 4 (SLC27A4) interaction partners

1. SLC27A4 gene mutation is responsible in the diagnosis of ichthyosis (show LBR Antibodies) prematurity syndrome in a premature infant.

2. expand the mutational repertory of FATP4 with three undescribed pathogenic mutations in two families

3. The results have interesting implications that SLC27A4/ATG4B (show ATG4B Antibodies) complex might be conducive to the occurrence of autophagy in human cancer cells, which is meaningful investigations toward the aim of developing autophagy-targeting drugs and have significant values in clinical application.

4. we resequenced the SLC27A3 (show FATP3 Antibodies) and SLC27A4 genes using 267 autism spectrum disorders(ASD (show ARSD Antibodies)) patient and 1140 control samples and detected 47 and 30 variants for the SLC27A3 (show FATP3 Antibodies) and SLC27A4, revealing that they are highly polymorphic with multiple rare variants.

5. We describe two siblings with ichthyosis (show LBR Antibodies) prematurity syndrome and report a recurrent homozygous mutation (c.1430T>A) that is predicted to lead to a p.Val477Asp substitution in fatty acid transport protein 4.

6. the cell surface protein (show CD28 Antibodies) CD36 (show CD36 Antibodies)/FAT directly facilitates fatty acid transport across the plasma membrane, whereas the intracellular acyl-CoA (show GNPAT Antibodies) synthetases FATP4 and ACSL1 (show Acsl1 Antibodies) enhance fatty acid uptake indirectly by metabolic trapping

7. the clinical implications of defects in these transporters and relevant animal models, including the FATP4 animal models and ichthyosis (show LBR Antibodies) prematurity syndrome, a congenital ichthyosis (show LBR Antibodies) caused by FATP4 deficiency. [review]

8. FATP4, ichthyin (show NIPAL4 Antibodies) and TGM1 (show TGM1 Antibodies) interact in lipid processing essential for maintaining the epidermal barrier function

9. FATP4 plays crucial roles in the development and maturation of both sebaceous and meibomian glands, as well as in the formation and composition of sebum

10. FATP1 and FATP4 proteins perform different functional roles in handling long chain fatty acids in skeletal muscle

Mouse (Murine) Solute Carrier Family 27 (Fatty Acid Transporter), Member 4 (SLC27A4) interaction partners

1. Transgenic expression of FATP1 in suprabasal keratinocytes rescued the phenotype of Fatp4 mutants, and FATP1 sorted to the same intracellular organelles as endogenous FATP4

2. a spontaneous Fatp4/Scl27a4 splice site mutation in congenital ichthyosis (show LBR Antibodies)

3. FATP4 plays crucial roles in the development and maturation of both sebaceous and meibomian glands, as well as in the formation and composition of sebum

4. A key role was demonstrated for FATP4 in oleic acide-induced GLP-1 (show GCG Antibodies) secretion from the murine intestinal L cell in vitro and in vivo.

5. even though hypoxia regulates the expression of FATP2 (show SLC27A2 Antibodies) and FATP4 in human trophoblasts, mouse Fatp2 (show SLC27A2 Antibodies) and Fatp4 are not essential for intrauterine fetal growth.

6. FATP4 contributes as an enzyme to the basal and insulin (show INS Antibodies)-mediated fatty acid uptake of CC muscle cells.

7. adipocyte-specific Fatp4 deficiency results in adipose hypertrophy and profound alterations in the metabolism of complex lipids.

8. Epidermal hyperproliferation in mice lacking FATP4 involves ectopic EGF receptor (show EGFR Antibodies) and Stat3 (show STAT3 Antibodies) signaling.

9. Fatp4-null mice displayed features of a neonatally lethal restrictive dermopathy. Lipid analysis demonstrated a disturbed fatty acid composition of epidermal ceramides.

10. FATP4 exhibits intrinsic acyl-coa synthetase activity and is a high velocity enzyme relative to FATP1.