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in the presence of Pax6 (show PAX6 Proteins)(S), beta(3) is translocated from the cytoplasm to the nucleus;full-length Ca(v)beta may act directly as a transcription regulator independent of its role in regulating Ca(2 (show CA2 Proteins)+) channel activity
Differential gene expression analysis identifies murine Cacnb3 as strongly upregulated in distinct dendritic cell populations upon stimulation
neither Ca(V)beta3 nor Ca(V)beta4 are indispensable for hair cell Ca(2 (show CA2 Proteins)+) currents but contribute to the overall current properties
Mice with cardiac-specific sequestration of the beta-subunit (show POLG Proteins) of the L-type calcium channel
Down-regulation of Cacnb3 expression does not rescue placental hyperplasia in a model of interspecies hybrid placentas, indicaating that upregulation is a downstream event.
the involvement of voltage-dependent Ca2 (show CA2 Proteins)+ channels and importance of the beta3 subunit in olfactory signal transduction
Ca(V)beta(3) has only subtle effects on L-type Ca(2 (show CA2 Proteins)+) currents in ileum smooth muscle.
These results suggest a possibility that, unrelated to voltage-dependent Ca(2 (show CA2 Proteins)+) channels regulation, Ca(v)beta3 negatively regulates the NMDAR (show GRIN1 Proteins) activity in the hippocampus.
Modified sympathetic nerve system activity with overexpression of the voltage-dependent calcium channel (show CACNA1I Proteins) beta3 subunit.(
Deficiency in beta3 regulatory subunit of voltage-gated calcium channels resulted in a profound survival defect of CD8 (show CD8A Proteins)(+) T cells.
This gene encodes a regulatory beta subunit of the voltage-dependent calcium channel. Beta subunits are composed of five domains, which contribute to the regulation of surface expression and gating of calcium channels and may also play a role in the regulation of transcription factors and calcium transport.
voltage-dependent calcium channel beta subunit
, calcium channel, voltage-dependent, beta 3 subunit
, voltage-dependent calcium channel beta 3b subunit
, voltage-dependent L-type calcium channel subunit beta-3
, voltage-dependent L-type calcium channel subunit beta-3-like
, calcium channel voltage-dependent subunit beta 3
, calcium channel beta 3 subunit
, Calcium channel subunit beta 3
, voltage-dependent calcium channel beta 3a