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Browse our anti-Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) Antibodies

Full name:: anti-Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) Antibodies (SGCB)

On www.antibodies-online.com are 63 Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) Antibodies from 19 different suppliers available. Additionally we are shipping Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) Proteins (12) and and many more products for this protein. A total of 81 Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) products are currently listed.

Synonyms:: 43kDa, A3b, AI747103, AI844814, beta-sarcoglycan, beta-SG, CG5657, Dmel\\CG5657, DmSCG-beta, dscgbeta, fa03a05, LGMD2E, scg-beta, SGC, wu:fa03a05, zgc:110833

list all antibodies	Gene Name	GeneID	UniProt
	SGCB	6443	Q16585
	SGCB	24051	P82349
	SGCB	680229
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Most Popular Reactivities for anti-Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) Antibodies

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Top referenced anti-Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) Antibodies

Human Polyclonal SGCB Primary Antibody for IHC, IHC (p) - ABIN4284180 : Pozsgai, Griffin, Heller, Mendell, Rodino-Klapac: β-Sarcoglycan gene transfer decreases fibrosis and restores force in LGMD2E mice. in Gene therapy 2016 (PubMed)
Show all 4 Pubmed References
Human Polyclonal SGCB Primary Antibody for ICC, IF - ABIN5075289 : Siemionow, Cwykiel, Heydemann, Garcia, Marchese, Siemionow, Szilagyi: Dystrophin Expressing Chimeric (DEC) Human Cells Provide a Potential Therapy for Duchenne Muscular Dystrophy. in Stem cell reviews 2018 (PubMed)

More Antibodies against Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) Interaction Partners

Human Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) interaction partners

This study demonstrated that LGMD2E is the most common type of sarcoglycanopathies in the Iranian population.
Clinical severity of limb-girdle muscular dystrophy type 2Emay be predicted by SGCB gene mutation and sarcoglycan protein expression.
Defective assembly of sarcoglycan complex in patients with beta-sarcoglycan gene mutations
beta-sarcoglycan and SPATA18 may have a role in limb-girdle muscular dystrophy type 2E
While the quantity of beta-sarcoglycan was nearly normal in the limb girdle muscular dystrophy (LGMD)2E carrier, the levels of dysferlin protein were reduced to 50% of controls in the carriers of LGMD2B.
These data suggest that formation of the beta-delta-core may promote the export and deposition of sarcoglycan subcomplexes at the plasma membrane, and therefore identifies a mechanism for sarcoglycan transport.
The limb-girdle muscular dystrophy patients with beta-sarcoglycan deficient LGMD2E do not enable an accurate prediction of the genotype.

Mouse (Murine) Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) interaction partners

Generate a new knock-in model carrying the missense mutation T151R in the beta-sarcoglycan gene since this is the second sarcoglycan protein with the most frequently reported missense mutations. Muscle analysis, performed at the age of 4 and 9-months, showed the presence of the mutated beta-sarcoglycan protein and of the other components of the dystrophin-associated glycoprotein complex at the muscle membrane.
beta-Sarcoglycan deficiency reduces atherosclerotic plaque formation in ApoE-knockout mouse model.
In Sgcb-null mice, severe morphological disruption was present from 4 weeks in both quadriceps and diaphragm, and included conspicuous deposition of extracellular matrix components.
Aging leads to changes in expression of beta-sarcoglycan in aged affected muscles (diaphragm and limb).
Sarcoglycan beta missense mutations affect sarcoglycan complex assembly and/or localization to the cell surface and provide information on the molecular mechanisms underlying the effects of various sarcoglycan mutations in muscular dystrophies.
Data demonstrate a novel function of the sarcoglycan complex in whole body glucose homeostasis and skeletal muscle metabolism, suggesting that the impairment of the skeletal muscle metabolism influences the pathogenesis of muscular dystrophy.

Fruit Fly (Drosophila melanogaster) Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) interaction partners

subcellular localization of dScgbeta dramatically changes during mitosis through possible association with tubulin; these observations point to a complex role of sarcoglycans in non-muscle tissues.

Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) Antigen Profile

Antigen Summary

This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.

Alternative names and synonyms associated with Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB)

sarcoglycan beta (SGCB) antibody
sarcoglycan, beta (dystrophin-associated glycoprotein) (Sgcb) antibody
Sarcoglycan beta (Scgbeta) antibody
SarcoGlycaN (sgn-1) antibody
uncharacterized LOC5567384 (LOC5567384) antibody
beta-sarcoglycan (CpipJ_CPIJ006944) antibody
sarcoglycan, beta (Sgcb) antibody
sarcoglycan beta L homeolog (sgcb.L) antibody
sarcoglycan beta (Sgcb) antibody
sarcoglycan, beta (dystrophin-associated glycoprotein) (sgcb) antibody

43kDa antibody
A3b antibody
AI747103 antibody
AI844814 antibody
beta-sarcoglycan antibody
beta-SG antibody
CG5657 antibody
Dmel\\CG5657 antibody
DmSCG-beta antibody
dscgbeta antibody
fa03a05 antibody
LGMD2E antibody
scg-beta antibody
SGC antibody
wu:fa03a05 antibody
zgc:110833 antibody

Protein level used designations for SGCB

43 kDa dystrophin-associated glycoprotein , 43DAG , beta-SG , beta-sarcoglycan , beta-sarcoglycan(43kD dystrophin-associated glycoprotein) , limb girdle muscular dystrophy 2E (non-linked families) , sarcoglycan, beta (43kD dystrophin-associated glycoprotein) , sarcoglycan beta , CG5657-PA , Scgbeta-PA , beta-sarcolgycan , SarcoGlycaN family member (sgn-1)

GENE ID	SPECIES
6443	Homo sapiens
24051	Mus musculus
41525	Drosophila melanogaster
184162	Caenorhabditis elegans
5567384	Aedes aegypti
6039376	Culex quinquefasciatus
100009208	Oryctolagus cuniculus
100172796	Pongo abelii
535372	Bos taurus
680229	Rattus norvegicus
100127262	Xenopus laevis
422760	Gallus gallus
100135674	Sus scrofa
100723371	Cavia porcellus
559788	Danio rerio

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