Browse our anti-Dual Specificity Phosphatase 3 (DUSP3) Antibodies

Full name:: anti-Dual Specificity Phosphatase 3 Antibodies (DUSP3)

On www.antibodies-online.com are 93 Dual Specificity Phosphatase 3 (DUSP3) Antibodies from 21 different suppliers available. Additionally we are shipping Dual Specificity Phosphatase 3 Proteins (16) and Dual Specificity Phosphatase 3 Kits (6) and many more products for this protein. A total of 119 Dual Specificity Phosphatase 3 products are currently listed.

Synonyms:: 2210015O03Rik, 5031436O03Rik, dusp3, RGD1560049, si:bz18k17.3, si:rp71-18k17.3, T-DSP11, VHR

list all antibodies	Gene Name	GeneID	UniProt
	DUSP3	1845	P51452
	DUSP3	498003
	DUSP3	72349	Q9D7X3
Show all species Show all synonyms

Most Popular Reactivities for anti-Dual Specificity Phosphatase 3 (DUSP3) Antibodies

Select your species and application

anti-Human Antibodies:

anti-Rat (Rattus) Antibodies:

anti-Mouse (Murine) Antibodies:

All available anti-Dual Specificity Phosphatase 3 Antibodies

Go to our pre-filtered search.

Relevant Pathways for anti-Dual Specificity Phosphatase 3 Antibodies

Toll-Like Receptors Cascades

More product categories related to Dual Specificity Phosphatase 3 Antibody

Top referenced anti-Dual Specificity Phosphatase 3 Antibodies

Human Polyclonal DUSP3 Primary Antibody for IHC (p), WB - ABIN392924 : Wang, Yeh, Chou, Yang, Fu, Chen, Cheng, Huang, Liu, Huang, Chen: Vaccinia H1-related phosphatase is a phosphatase of ErbB receptors and is down-regulated in non-small cell lung cancer. in The Journal of biological chemistry 2011 (PubMed)

More Antibodies against Dual Specificity Phosphatase 3 Interaction Partners

Human Dual Specificity Phosphatase 3 (DUSP3) interaction partners

Nuclear HSP70 (show HSP70 Antibodies) leads to enhancement of vaccinia H1-related phosphatase (VHR) activity via protein-protein interaction rather than its molecular chaperone (show HSP90AA1 Antibodies) activity, thereby suppressing excessive ERK (show EPHB2 Antibodies) activation. Downregulation of either VRK3 or HSP70 (show HSP70 Antibodies) rendered cells vulnerable to glutamate (show GRIN1 Antibodies)-induced apoptosis.
Data indicated that regulating non-receptor tyrosine kinase (show TNK1 Antibodies) FAK (show PTK2 Antibodies) and cell migration is a newly revealed function of VHR/DUSP3.
The loss of DUSP3 activity markedly increases gamma radiation-induced DNA strand breaks, suggesting a potential novel role for DUSP3 in DNA repair.
In PTP1B (show PTPN1 Antibodies) and VHR, two new allosteric clusters were identified in each enzyme.
In the phosphatase-silenced cells, the normal bipolar spindle structure was restored by chemical inhibition of Erk1/2 and ectopic overexpression of Dusp3. We propose that at M phase Dusp3 keeps Erk1/2 activity in check to facilitate normal mitosis.
Data suggest levels of gene expression of both DUSP3 (dual specificity phosphatase 3) and PSME3 (proteasome activator subunit 3 (show PSME3 Antibodies)) are associated with susceptibility to Staphylococcus aureus infection/sepsis in humans and in mouse disease model.
Our results demonstrate that DUSP3 plays a key and nonredundant role as a regulator of innate immune responses
VHR can dimerize inside cells, and that VHR catalytic activity is reduced upon dimerization.
DUSP3 is a pro-angiogenic atypical dual-specificity phosphatase.
DUSP3 interacting partners are nucleolar proteins involved in processes related to DNA repair and senescence.

Mouse (Murine) Dual Specificity Phosphatase 3 (DUSP3) interaction partners

Data indicated that regulating non-receptor tyrosine kinase (show TNK1 Antibodies) FAK (show PTK2 Antibodies) and cell migration is a newly revealed function of VHR/DUSP3.
DUSP3 phosphatase plays a key role in metastatic growth.
At the molecular level, DUSP3 deletion was associated with estrogen-dependent decreased phosphorylation of ERK1/2 and Akt (show AKT1 Antibodies) in peritoneal macrophages stimulated ex vivo by LPS (show TLR4 Antibodies); results demonstrate that estrogens may modulate M2-like responses during endotoxemia in a DUSP3-dependent manner
Data suggest levels of gene expression of both Dusp3 (dual specificity phosphatase 3) and Psme3 (proteasome activator subunit 3 (show PSME3 Antibodies)) are associated with susceptibility to Staphylococcus aureus infection/sepsis in humans and in mouse disease model.
Platelets from DUSP3-deficient mice displayed a selective impairment of aggregation and granule secretion.
Our results demonstrate that DUSP3 plays a key and nonredundant role as a regulator of innate immune responses
DUSP3 is a pro-angiogenic atypical dual-specificity phosphatase.

Dual Specificity Phosphatase 3 (DUSP3) Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1.

Alternative names and synonyms associated with Dual Specificity Phosphatase 3 (DUSP3)

dual specificity phosphatase 3 (DUSP3) antibody
dual specificity phosphatase 3b (dusp3b) antibody
dual specificity phosphatase 3 (Dusp3) antibody
dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) (Dusp3) antibody

2210015O03Rik antibody
5031436O03Rik antibody
dusp3 antibody
RGD1560049 antibody
si:bz18k17.3 antibody
si:rp71-18k17.3 antibody
T-DSP11 antibody
VHR antibody

Protein level used designations for DUSP3

dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) , dual specificity phosphatase 3 , dual specificity protein phosphatase 3 , dual specificity protein phosphatase VHR , serine/threonine specific protein phosphatase , vaccinia H1-related phosphatase , vaccinia virus phosphatase VH1-related

GENE ID	SPECIES
425527	Gallus gallus
468271	Pan troglodytes
568344	Danio rerio
713686	Macaca mulatta
1845	Homo sapiens
498003	Rattus norvegicus
480505	Canis lupus familiaris
615432	Bos taurus
72349	Mus musculus

Selected quality suppliers for anti-Dual Specificity Phosphatase 3 (DUSP3) Antibodies

Did you look for something else?

Phone:	+1 877 302 8632
Fax:	+1 888 205 9894 (Toll-free)
E-Mail:	orders@antibodies-online.com

Show all anti-Dual Specificity Phosphatase 3 (DUSP3) Antibodies with Pubmed References

Human Dual Specificity Phosphatase 3 (DUSP3) interaction partners

Mouse (Murine) Dual Specificity Phosphatase 3 (DUSP3) interaction partners

Antigen Summary

Alternative names and synonyms associated with Dual Specificity Phosphatase 3 (DUSP3)

Protein level used designations for DUSP3