Browse our anti-CD40 (CD40) Antibodies

Full name:: anti-CD40 Molecule, TNF Receptor Superfamily Member 5 Antibodies (CD40)

On www.antibodies-online.com are 920 CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) Antibodies from 36 different suppliers available. Additionally we are shipping CD40 Kits (65) and CD40 Proteins (65) and many more products for this protein. A total of 1078 CD40 products are currently listed.

Synonyms:: AI326936, Bp50, CDW40, GP39, HIGM1, IGM, IMD3, p50, T-BAM, Tnfrsf5, TNFSF5, TRAP

list all antibodies	Gene Name	GeneID	UniProt
	CD40	958	P25942
	CD40	21939	P27512
	CD40	171369
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Most Popular Reactivities for anti-CD40 (CD40) Antibodies

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Top referenced anti-CD40 Antibodies

Mouse (Murine) Monoclonal CD40 Primary Antibody for FACS - ABIN2689247 : Akiba, Oshima, Takeda, Atsuta, Nakano, Nakajima, Nohara, Yagita, Okumura: CD28-independent costimulation of T cells by OX40 ligand and CD70 on activated B cells. in Journal of immunology (Baltimore, Md. : 1950) 1999 (PubMed)
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Mouse (Murine) Monoclonal CD40 Primary Antibody for BR, FACS - ABIN1176841 : Leifeld, Trautwein, Dumoulin, Manns, Sauerbruch, Spengler: Enhanced expression of CD80 (B7-1), CD86 (B7-2), and CD40 and their ligands CD28 and CD154 in fulminant hepatic failure. in The American journal of pathology 1999 (PubMed)
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Mouse (Murine) Monoclonal CD40 Primary Antibody for IHC (f), IHC (fro) - ABIN2689244 : Bourgeois, Rocha, Tanchot: A role for CD40 expression on CD8+ T cells in the generation of CD8+ T cell memory. in Science (New York, N.Y.) 2002 (PubMed)
Show all 13 Pubmed References
Mouse (Murine) Monoclonal CD40 Primary Antibody for IHC (f), IHC (fro) - ABIN1176971 : French, Chan, Tutt, Glennie: CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help. in Nature medicine 1999 (PubMed)
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Mouse (Murine) Monoclonal CD40 Primary Antibody for FACS - ABIN2689248 : Grewal, Flavell: CD40 and CD154 in cell-mediated immunity. in Annual review of immunology 1998 (PubMed)
Show all 11 Pubmed References
Human Monoclonal CD40 Primary Antibody for Func, FACS - ABIN786601 : Bates, Fournier, Garcia, Valladeau, Durand, Pin, Zurawski, Patel, Abrams, Lebecque, Garrone, Saeland: APCs express DCIR, a novel C-type lectin surface receptor containing an immunoreceptor tyrosine-based inhibitory motif. in Journal of immunology (Baltimore, Md. : 1950) 1999 (PubMed)
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Human Monoclonal CD40 Primary Antibody for FACS - ABIN786600 : Björck, Paulie: CD40 antibodies defining distinct epitopes display qualitative differences in their induction of B-cell differentiation. in Immunology 1996 (PubMed)
Show all 10 Pubmed References
Mouse (Murine) Monoclonal CD40 Primary Antibody for Func, FACS - ABIN1169011 : Rolink, Andersson, Melchers: Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity. in European journal of immunology 1998 (PubMed)
Show all 8 Pubmed References
Human Monoclonal CD40 Primary Antibody for FACS - ABIN1384052 : Geissmann, Revy, Regnault, Lepelletier, Dy, Brousse, Amigorena, Hermine, Durandy: TGF-beta 1 prevents the noncognate maturation of human dendritic Langerhans cells. in Journal of immunology (Baltimore, Md. : 1950) 1999 (PubMed)
Show all 8 Pubmed References
Human Monoclonal CD40 Primary Antibody for FACS - ABIN1384053 : Metcalfe, McIntosh, Marelli-Berg, Lombardi, Lechler, Weetman: Detection of CD40 on human thyroid follicular cells: analysis of expression and function. in The Journal of clinical endocrinology and metabolism 1998 (PubMed)
Show all 8 Pubmed References

More Antibodies against CD40 Interaction Partners

Human CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) interaction partners

CD40 gene rs4810485 and rs1883832 mutations investigated in Recurrent aphthous stomatitis patients.
these data demonstrated that miR (show MLXIP Antibodies)-145-5p may function as a cardiac-protective molecule in myocardial ischemic injury by ameliorating inflammation and apoptosis via negative regulation of CD40.
rs4810485 G>T and rs1883832 C >T SNPs in the CD40 gene may be associated with disease susceptibility and severity in knee osteoarthritis in the Chinese Han population.
Data show that all the six inflammation-related CpG-SNPs genotypes including IL1B (show IL1B Antibodies) rs16944, IL1R2 (show IL1R2 Antibodies) rs2071008, PLA2G7 (show Lp-PLA2 Antibodies) rs9395208, FAM5C rs12732361, CD40 rs1800686, and CD36 (show CD36 Antibodies) rs2065666 were associated with coronary heart disease (CHD (show CHDH Antibodies)), suggesting an important role of inflammation in the risk of CHD (show CHDH Antibodies).
miR (show MLXIP Antibodies)-145 is involved in the anti-proliferation and anti-inflammation effects of aspirin on vascular smooth muscle cells by inhibiting the expression of CD40.
selective knockdown of TNFR5 ameliorates glucolipotoxic induction of STAT1 (show STAT1 Antibodies) expression and NF-kappaB (show NFKB1 Antibodies) activity.
CD40 signaling in adipose tissue macrophages regulates major histocompatibility complex class II and CD86 (show CD86 Antibodies) expression to control the expansion of CD4 (show CD4 Antibodies)(+) T cells.
CD40 activation resulted in down-regulation of Thioredoxin (Trx)-1 (show TXN Antibodies) to permit ASK1 (show MAP3K5 Antibodies) activation and apoptosis. Although soluble receptor (show IFNAR1 Antibodies) agonist alone could not induce death, combinatorial treatment incorporating soluble CD40 agonist and pharmacological inhibition of Trx-1 (show MLL Antibodies) was functionally equivalent to the signal triggered by mCD40L.
autologous CD4 (show CD4 Antibodies)(+) T cells that are exposed to EVs from CD40/IL-4 (show IL4 Antibodies)-stimulated CLL cells exhibit enhanced migration, immunological synapse signaling, and interactions with tumor cells.
Cytokine expression upon simultaneous stimulation of TSHR and CD40 is greater than levels achieved with TSH or CD40L alone. Increased expression of CD40 by TSH is a potential mechanism for this process

Mouse (Murine) CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) interaction partners

Results suggest that platelet CD40 plays a pivotal role in neointima formation after arterial injury
CD73 expression identifies a subset of IgM (show CD40LG Antibodies)(+) antigen-experienced cells with memory attributes that is T cell and CD40 signalling dependent
CD40 silencing with a specific siRNA ameliorates progression of experimental atherosclerosis in ApoE (show APOE Antibodies)(-/-) mice via NF-kappaB (show NFKB1 Antibodies)/miR (show MLXIP Antibodies)-125b signaling axis.
CD40 functions as a non-redundant mechanism to convert the tumor microenvironment immunologically.
selective knockdown of TNFR5 ameliorates glucolipotoxic induction of STAT1 (show STAT1 Antibodies) expression and NF-kappaB (show NFKB1 Antibodies) activity.
CD40 plays a critical role in the pathogenesis of type 1 diabetes, influencing lymphocyte trafficking, T-cell receptor expression, and T-cell pathogenesis.
CD40 signaling in adipose tissue macrophages regulates major histocompatibility complex class II and CD86 (show CD86 Antibodies) expression to control the expansion of CD4 (show CD4 Antibodies)(+) T cells.
Adoptively transferred Th40 cells (CD4 (show CD4 Antibodies)+CD40+ Tcells) are present in lesions in the CNS and are associated with wide spread demyelination.
this study reports that anti-CD40 mAb administration <3 d in advance of chemotherapy is lethal in more than half of treated C57BL/6 mice in pancreatic cancer model
The data show that CD40-mediated inhibition of PC generation is via engagement of multiple pathway and constitutive CD40 signaling in vivo involving bystander T-B interactions can calibrate B cell differentiation outcomes

Pig (Porcine) CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) interaction partners

These results therefore may help understand the molecular mechanism of CD40L (show CD40LG Antibodies) signaling that contributes to the pathophysiology of atherosclerosis.
This study shows that xenogeneic interaction between hCD40L and pCD40 can activate porcine endothelial cells through NF-kappaB (show NFKB1 Antibodies) signaling.
The appearance of CD25 (show IL2RA Antibodies) after activation of porcine dendritic cells, is reported.

Cow (Bovine) CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) interaction partners

Results demonstrated greater CD40 and CD40L (show CD40LG Antibodies) expression on fresh mononuclear leukocytes obtained from animals in the clinical stage of Johne's Disease.
study investigated the hypothesis that CD40 signalling is impaired in Mycobacterium avium subspecies paratuberculosis-infected macrophages

CD40 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Alternative names and synonyms associated with CD40

CD40 molecule (CD40) antibody
CD40 antigen (Cd40) antibody
CD40 molecule (Cd40) antibody

AI326936 antibody
Bp50 antibody
CDW40 antibody
GP39 antibody
HIGM1 antibody
IGM antibody
IMD3 antibody
p50 antibody
T-BAM antibody
Tnfrsf5 antibody
TNFSF5 antibody
TRAP antibody

Protein level used designations for CD40

B cell surface antigen CD40 , B cell-associated molecule , B-cell surface antigen CD40 , CD40 antigen (TNF receptor superfamily member 5) , CD40 type II isoform , CD40L receptor , nerve growth factor receptor-related B-lymphocyte activation molecule , tumor necrosis factor receptor superfamily member 5 , tumor necrosis factor receptor superfamily, member 5 , T-cell differentiation antigen , human CD40-homologue , CD40 antigen, TNF receptor superfamily member 5

GENE ID	SPECIES
958	Homo sapiens
403469	Canis lupus familiaris
21939	Mus musculus
395385	Gallus gallus
397395	Sus scrofa
171369	Rattus norvegicus
100034049	Equus caballus
286849	Bos taurus
100349106	Oryctolagus cuniculus
100385800	Callithrix jacchus
100728791	Cavia porcellus
443232	Ovis aries
707749	Macaca mulatta

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Show all anti-CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) Antibodies with Pubmed References