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anti-Rat (Rattus) EGF Antibodies:
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anti-Mouse (Murine) EGF Antibodies:
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Human Polyclonal EGF Primary Antibody for IHC, IHC (p) - ABIN446990
Sette, Salvati, Memeo, Fecchi, Colarossi, Di Matteo, Signore, Biffoni, DAndrea, De Antoni, Canzonieri, De Maria, Eramo: EGFR inhibition abrogates leiomyosarcoma cell chemoresistance through inactivation of survival pathways and impairment of CSC potential. in PLoS ONE 2012
Show all 3 Pubmed References
Human Monoclonal EGF Primary Antibody for IHC, ELISA - ABIN969091
Soubeyran, Kowanetz, Szymkiewicz, Langdon, Dikic: Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors. in Nature 2002
Show all 3 Pubmed References
Mouse (Murine) Polyclonal EGF Primary Antibody for IHC (p), WB - ABIN3042717
Ge, Yu, Petitte, Zhang: Epidermal growth factor-induced proliferation of chicken primordial germ cells: involvement of calcium/protein kinase C and NFKB1. in Biology of reproduction 2009
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Mouse (Murine) Polyclonal EGF Primary Antibody for IF (p), IHC (p) - ABIN1385702
Niwa, Nishibori, Hamasaki, Kobori, Liu, Wake, Mori, Yoshino, Takahashi: Voluntary exercise induces neurogenesis in the hypothalamus and ependymal lining of the third ventricle. in Brain structure & function 2015
Human Monoclonal EGF Primary Antibody for IHC, ELISA - ABIN966031
Gual, Giordano, Williams, Rocchi, Van Obberghen, Comoglio: Sustained recruitment of phospholipase C-gamma to Gab1 is required for HGF-induced branching tubulogenesis. in Oncogene 2000
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Human Monoclonal EGF Primary Antibody for IF, ELISA - ABIN966030
Yacoub, McKinstry, Hinman, Chung, Dent, Hagan: Epidermal growth factor and ionizing radiation up-regulate the DNA repair genes XRCC1 and ERCC1 in DU145 and LNCaP prostate carcinoma through MAPK signaling. in Radiation research 2003
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Mouse (Murine) Polyclonal EGF Primary Antibody for WB - ABIN223520
Munoz, Rodriguez-Cruz, Greco, Nagula, Scotto, Rameshwar: Temozolomide induces the production of epidermal growth factor to regulate MDR1 expression in glioblastoma cells. in Molecular cancer therapeutics 2014
Human Polyclonal EGF Primary Antibody for Neut, WB - ABIN223519
Lewy, Ryan, Read, Fong, Poole, Seed, Sharma, Smith, Kwan, Stewart, Bacon, Warfield, Franklyn, McCabe, Boelaert: Regulation of pituitary tumor transforming gene (PTTG) expression and phosphorylation in thyroid cells. in Endocrinology 2013
Human Monoclonal EGF Primary Antibody for ICC, ELISA - ABIN1724732
Gout, Dhand, Panayotou, Fry, Hiles, Otsu, Waterfield: Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression system. in The Biochemical journal 1993
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Dog (Canine) Polyclonal EGF Primary Antibody for WB - ABIN2776844
Teixeira, Ribeiro, Cardoso, Pinto, Lobo, Fraga, Pina, Calais-da-Silva, Medeiros: Genetic polymorphism in EGF is associated with prostate cancer aggressiveness and progression-free interval in androgen blockade-treated patients. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008
Zebrafish scube1 (show SCUBE1 Antibodies) (signal peptide-CUB (complement protein C1r (show C1R Antibodies)/C1s (show C1S Antibodies), Uegf, and Bmp1 (show BMP1 Antibodies))-EGF (epidermal growth factor) domain-containing protein 1) is involved in primitive hematopoiesis
EGF is likely a potential paracrine/juxtacrine factor from the oocytes to regulate the function of the follicle cells.
These results suggest that there is an EGF signaling network in the zebrafish ovarian follicle, and the functionality of this network is self-regulated by its own members.
novel EGFR (show EGFR Antibodies)-NF-kappaB (show NFKB1 Antibodies)-FOXC1 (show FOXC1 Antibodies) signaling axis that is critical for BLBC cell function
EGFR (show EGFR Antibodies) pathway gene expression analysis indicated that DeltaNp63 alters EGFR (show EGFR Antibodies)-regulated genes involved in cell adhesion, migration, and angiogenesis. Addition of EGF or neutralizing EGFR (show EGFR Antibodies) antibodies demonstrated that EGFR (show EGFR Antibodies) activation is responsible for DeltaNp63-mediated loss of cellular adhesion
EGF up-regulated CCL2 (show CCL2 Antibodies) expression in HNSCC cells, which recruited monocytes and turned them into M2-like macrophages, thus forming a positive feedback paracrine loop.
this study shows that EGF induces epithelial-mesenchymal transition through phospho-Smad2 (show SMAD2 Antibodies)/3-Snail (show SNAI1 Antibodies) signaling pathway in breast cancer cells
EGF and TNFalpha (show TNF Antibodies) cooperatively promoted the motility of HCC (show FAM126A Antibodies) cells mainly through NF-kappaB (show NFKB1 Antibodies)/p65 (show GORASP1 Antibodies) mediated synergistic induction of FN in vitro. These findings highlight the crosstalk between EGF and TNFalpha (show TNF Antibodies) in promoting HCC (show FAM126A Antibodies), and provide potential targets for HCC (show FAM126A Antibodies) prevention and treatment.
Data suggest that EGF induces colorectal cancer cells to undergo epithelial-mesenchymal transition, enhances their ability to invade/migrate, and promotes phosphorylation of Ezrin (show EZR Antibodies) at Tyr353. (EGF = epidermal growth factor)
Simulation results indicate that human epidermal growth factor receptor (show EGFR Antibodies) (hEGFR) soluble soluble extracellular domains (sECD):EGF show different dynamic properties between the two pHs (show PCBD1 Antibodies), and the complex may have a higher tendency of activation at pH 8.5.
EGF and IP-10 (show CXCL10 Antibodies) were significantly elevated and GRO (show CXCL1 Antibodies) levels were lower in the tear profile of HIV patients with dry eye disease (DED (show AATF Antibodies)) compared to immunocompetent patients with DED (show AATF Antibodies).
Data (including data from studies using transgenic/knockout mice) suggest that surfactant protein A1 (SPA1) interferes with EGF binding to EGFR (show EGFR Antibodies) in pulmonary alveoli cell lines; SPA1 (show SIPA1 Antibodies) directly binds extracellular domain of EGFR (show EGFR Antibodies); binding of SPA1 (show SIPA1 Antibodies) to EGFR (show EGFR Antibodies) appears to be different from binding of SPD (show HOXD13 Antibodies) to EGFR (show EGFR Antibodies); binding of SPA1 (show SIPA1 Antibodies) to EGFR (show EGFR Antibodies) does not suppress EGF-induced phosphorylation of EGFR (show EGFR Antibodies) or cell proliferation.
EGF-AREG (show AREG Antibodies) interplay in airway basal cell stem/progenitor cells is one of the mechanisms that mediates the interconnected pathogenesis of all major smoking-induced lesions in the human airway epithelium.
hijacks miR (show MLXIP Antibodies)-198/FSTL1 (show FSTL1 Antibodies) wound-healing switch and steers a two-pronged pathway toward metastasis
These results indicate that Kindlin-1 (show FERMT1 Antibodies) is essential in EGF-induced re-epithelialization in skin wound healing and provide additional rationale for the clinical application of EGF in the treatment of acute wounds.
concentration of EGF is critical for the switch between hair follicle growth and inhibition, and EGF promotes DP cell proliferation via Notch (show NOTCH1 Antibodies) signaling pathway
EGF promotes FoxM1 (show FOXM1 Antibodies) expression through the ERK (show EPHB2 Antibodies) signal pathway
Data indicate that Sonic hedgehog (Shh (show SHH Antibodies)) stimulate branching morphogenesis (BrM (show SMARCA2 Antibodies)) and induced synthesis of mRNAs for Ptch1 (show PTCH1 Antibodies) protein, epidermal growth factor (EGF) and receptors of the ErbB (show EGFR Antibodies) receptors ErbB1 (show EGFR Antibodies), ErbB2 (show ERBB2 Antibodies) and ErbB3 (show ERBB3 Antibodies).
Either LIF (show LIF Antibodies) or EGF is needed during development of pre-implantation embryo.
PXR (show NR1I2 Antibodies) activation stimulates EGF-mediated hepatocyte proliferation in mice, at least in part, through inhibiting FOXO3 (show FOXO3 Antibodies) from accelerating cell-cycle progression.
Data (including data from studies in knockout mice) suggest that Epab (embryonic poly(A)-binding protein), which is oocyte specific, is required for ability of cumulus cells and granulosa cells to exhibit responsiveness to Egf/Egfr (show EGFR Antibodies) signaling.
modulation of EGF signaling affects in vitro expansion and differentiation of progenitors from embryonic pancreas of both mice and man.
TLR4 (show TLR4 Antibodies) blockade prevented TPN (show TAPBP Antibodies)-associated intestinal mucosa atrophy by preserving proliferation and preventing apoptosis. This is driven by a reduction in TNF-alpha (show TNF Antibodies) abundance and increased EGF.
Interval between litters and litter size may be linked with EGF polymorphisms in pigs.
10 nM/L EGF was the optimal dose for serum-free culture, which can replace traditional standard serum medium for in vitro expansion of miniature pig bone marrow-derived mesenchymal stem cells.
EGF coordinately activates multiple cell signaling pathways critical to proliferation, migration and survival of trophectoderm cells.
progesterone-induced TACE/ADAM17 (show ADAM17 Antibodies) leads to production of soluble EGF domain from cumulus cells, which enhances functional changes of cumulus cells and progresses meiotic maturation of oocytes
The phase-related expression of EGF and EGFR (show EGFR Antibodies) in the endothelium of the uterine artery and its branches suggest the modulatory effect of EGF and its receptor on the uterine artery and the region supplying these vessels.
EGF appears to sensitize epithelial cells to the detrimental effects of IFN-alpha (show IFNA Antibodies) but also helps to restore barrier function in the healing phase.
analysis of EGF in dairy cows reveals increased EGF concentrations for 2-3 days between Days 2 and 5
Data suggest that EGF expression in endometrium varies by species and parity; in Japanese Black cows, EGF expression is consistently high, while in Holstein cows, EGF expression is down-regulated in postpartum period after second calving.
Data suggest that epidermal growth factor receptor (show EGFR Antibodies) B [ErbB (show EGFR Antibodies)] isoforms and their ligands (epidermal growth factor [EGF], amphiregulin (show AREG Antibodies) [AREG (show AREG Antibodies)], and neuregulin-1 (show NRG1 Antibodies) [NRG1 (show NRG1 Antibodies)]) are expressed in uteroplacental tissues in mid- and late-phases of pregnancy.
EGF plays a role during bovine placentation.
Data suggest that epidermal growth factor (EGF) and EGF receptors are important paracrine and/or autocrine regulators of spermatogenesis in bovine.
This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.
epidermal growth factor (beta-urogastrone)
, pro-epidermal growth factor
, Pro-epidermal growth factor precursor (EGF)