Browse our anti-IL1A (IL1A) Antibodies

Human Interleukin 1 alpha (IL1A) interaction partners

1. Meta-analysis suggests that the IL-1B (show IL1B Antibodies) rs16944 polymorphism is a susceptibility risk factor for febrile seizures in Caucasian and Asian populations. The IL-1B (show IL1B Antibodies) rs1143627, IL-1B (show IL1B Antibodies) rs1143634, and IL-1A rs1800587 polymorphisms are not associated with febrile seizure risk.

2. The IL-1b+3954 C/T polymorphism significantly increases RAS risk. In addition, the IL-10-1082 G/A polymorphism provided protective effects for RAS in the Asian population

3. The single nucleotide polymorphism (SNP) of IL-1beta (show IL1B Antibodies) gene (rs3917356G>A) increased the risk of HCC (show FAM126A Antibodies) in the recessive model (p<0.001, OR=2.58, 95% CI=1.53-4.33), whereas other SNPs in IL-1alpha and IL-1RA (show IL1RN Antibodies) showed no significant association between Hepatocellular carcinoma patients and controls.

4. our findings proposed an association between IL1A 4-bp ins (show INS Antibodies)/del polymorphism and risk of prostate cancer

5. effect of IL-22 (show IL22 Antibodies) on Intestinal Epithelial Cells responses may not be in inducing CXCL8 (show IL8 Antibodies) by itself, but in enhancing TNF-alpha (show TNF Antibodies)- and IL-1-induced CXCL8 (show IL8 Antibodies) secretion to augment the contribution of IECs to local inflammatory responses.

6. the present study was intended to determine whether single-nucleotide polymorphisms (SNPs) in the IL-1 gene cluster are also associated with periodontal disease in a Linkage disequilibrium analysis

7. No significant difference was seen in mRNA levels among different promoter genotype for IL1A in SCA3 (show ATXN3 Antibodies) patients vs. controls, except a previously reported higher level in those with the IL1A*T allele. These patients also showed an earlier age of onset than those homozygous for IL1A*C.

8. Obesity was associated with higher expression of NILCO molecules (Notch (show NOTCH1 Antibodies)-IL1-leptin (show LEP Antibodies)) in type II endometrial cancer.

9. through IL-1alpha production, airway epithelial cells induce a pro-inflammatory lung fibroblast phenotype that is further enhanced with cigarette smoke extract exposure in COPD (show ARCN1 Antibodies), suggesting an aberrant epithelial-fibroblast interaction in COPD (show ARCN1 Antibodies)

10. our study has described the association between rs3783550 (IL-1A), rs3783546 (IL-1A) and rs2853550 (IL-1B) and AS risk and between a new haplotype, "TCG", of rs3783550, rs3783546 and rs2853550 and AS in Chinese Han population.

Mouse (Murine) Interleukin 1 alpha (IL1A) interaction partners

1. Infection with Mycobacterium bovis results in increase in interleukin-1alpha, TGF-beta1 (show TGFB1 Antibodies), and MMP1 (show MMP1 Antibodies) in multinucleated macrophages.

2. Together, these data suggest that caspase-11 (show CASP4 Antibodies)/IL-1alpha pathway plays an important role in defending against Klebsiella pneumoniae by recruiting neutrophils in the early stage of infection.

3. These data highlight an important interdependency between the potent pro-inflammatory cytokine IL1A and Fshr (show FSHR Antibodies) expression.

4. Following vasectomy, IL1alpha, IL1beta (show IL1B Antibodies), IL1ra (show IL1RN Antibodies), IL10 (show IL10 Antibodies), and TNF-alpha (show TNF Antibodies) may mediate immune reaction in whole epididymis, whereas IL6 (show IL6 Antibodies) and TGF-beta1 (show TGFB1 Antibodies) may mediate regionally different immune response primarily in the lower part of epididymis.

5. Since neither IL-1alpha nor IL-1beta (show IL1B Antibodies) depletions completely rescued the phenotype, we believe that IL-1alpha and IL-1beta (show IL1B Antibodies) have a similar and probably complementary role in FHF progression

6. These results suggested that Streptococcus pneuomoniae PLY induces the influx of calcium in Streptococcus pneumoniae-infected macrophages, followed by calpain activation and subsequent IL-1alpha maturation and secretion.

7. our results suggest that mature IL-1alpha induced by hS100A7 is via RAGE (show AGER Antibodies)-p38 MAPK (show MAPK14 Antibodies) and calpain-1 (show CAPN1 Antibodies) pathway in keratinocyte and this mechanism may play an important role during psoriasis.

8. Il-1 signaling pathway has a key role in abdominal aortic aneurysm formation in mouse model of Kawasaki disease.

9. endothelial cells were identified as the primary cellular source of G-CSF (show CSF3 Antibodies) during OPC, which responded to IL-1alpha that was released from keratinocytes in the infected tissue.

10. As a dual function cytokine, IL-1alpha may contribute to the induction of CHOP (show DDIT3 Antibodies) intracellularly, while IL-1alpha released from necrotic cells accelerates steatohepatitis via induction of inflammatory cytokines by neighboring cells.

Pig (Porcine) Interleukin 1 alpha (IL1A) interaction partners

Cow (Bovine) Interleukin 1 alpha (IL1A) interaction partners

1. Protein kinase R plays a pivotal role in oncostatin M and interleukin-1 signalling in bovine articular cartilage chondrocytes.

2. Testicular IL-1 alpha and IL-1 beta (show IL1B Antibodies) concentrations were highest in the early post-natal period; however, IL-1 bioactivity and IL-6 (show IL6 Antibodies) concentrations were greatest in the immediate pre-pubertal period.

3. Genes for IL-1alpha and IL-1beta (show IL1B Antibodies) are expressed and a functional IL-1R is present in bovine corpora lutea throughout luteal phase. IL-1alpha and IL-1beta (show IL1B Antibodies) may have different roles as regulating PGF (show PGF Antibodies)(2alpha) and PGE (show LIPF Antibodies)(2) production during luteal phase.

4. non-metalloproteinase mechanisms participate in IL-1-induced matrix degradation and loss of tissue material properties

5. These results suggest that IL-1alpha and IL-1beta (show IL1B Antibodies) are produced by the stromal cells, that IL-1beta (show IL1B Antibodies) is produced by the epithelial cells, and that IL-1alpha is a more potent stimulator of prostaglandin and plasminogen (show PLG Antibodies) activator in bovine endometrial cells.

Rabbit Interleukin 1 alpha (IL1A) interaction partners