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MAP3K7 Antigen Profile
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2\; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alternative names and synonyms associated with MAP3K7
mitogen-activated protein kinase kinase kinase 7 (map3k7) ELISA Kit
mitogen activated protein kinase kinase kinase 7 (Map3k7) ELISA Kit
mitogen-activated protein kinase kinase kinase 7 (MAP3K7) ELISA Kit
mitogen-activated protein kinase kinase kinase 7 (Map3k7) ELISA Kit