RIPK1 ELISA Kits
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RIPK1 ELISA Kit (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1) ELISA Kit
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RIPK1 ELISA Kit (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1) ELISA Kit
RIPK1 ELISA Kit (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1) ELISA Kit
RIPK1 ELISA Kit (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1) ELISA Kit
RIPK1 ELISA Kit (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1) ELISA Kit
RIPK1 ELISA Kit (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1) ELISA Kit
RIPK1 Antigen Profile
Protein Summary
Serine-threonine kinase which transduces inflammatory and cell-death signals (necroptosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor. Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules. Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation. Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death. RIPK1 and RIPK3 association, in particular, forms a necroptosis-inducing complex.
Alternative names and synonyms associated with RIPK1
- receptor interacting serine/threonine kinase 1 (RIPK1) antibody
- receptor (TNFRSF)-interacting serine-threonine kinase 1 (Ripk1) antibody
- receptor interacting serine/threonine kinase 1 (Ripk1) antibody
- receptor interacting serine/threonine kinase 1 L homeolog (ripk1.L) antibody
- D330015H01Rik antibody
- Rinp antibody
- RIP antibody
- rip1 antibody
- ripk1 antibody
- xrip1 antibody
- xRIP1beta antibody
Protein level used designations for RIPK1
RIP-1 , cell death protein RIP , receptor interacting protein , receptor-interacting protein 1 , receptor-interacting serine/threonine-protein kinase 1 , serine/threonine-protein kinase RIP , receptor (TNFRSF)-interacting serine-threonine kinase 1 , receptor interacting serine/threonine kinase 1 L homeolog , receptor-interacting protein 1 beta
| GENE ID | SPECIES |
|---|---|
| 8737 | Homo sapiens |
| 19766 | Mus musculus |
| 100230522 | Taeniopygia guttata |
| 306886 | Rattus norvegicus |
| 504727 | Bos taurus |
| 100524751 | Sus scrofa |
| 734234 | Xenopus laevis |
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