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Human Polyclonal TGFA Primary Antibody for WB - ABIN3042615
Zhang, Chen, Qi, Wang, Xiao, Zhu: Inhibition of calcium-calmodulin-dependent kinase II suppresses cardiac fibroblast proliferation and extracellular matrix secretion. in Journal of cardiovascular pharmacology 2010
Show all 3 Pubmed References
Human Polyclonal TGFA Primary Antibody for Func, IHC (p) - ABIN2476746
Junier: What role(s) for TGFalpha in the central nervous system? in Progress in neurobiology 2000
Human Polyclonal TGFA Primary Antibody for WB - ABIN967168
Fallon, Reid, Kinyamu, Opole, Opole, Baratta, Korc, Endo, Duong, Nguyen, Karkehabadhi, Twardzik, Patel, Loughlin: In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain. in Proceedings of the National Academy of Sciences of the United States of America 2001
Human Polyclonal TGFA Primary Antibody for Neut, ELISA - ABIN223573
Lewy, Ryan, Read, Fong, Poole, Seed, Sharma, Smith, Kwan, Stewart, Bacon, Warfield, Franklyn, McCabe, Boelaert: Regulation of pituitary tumor transforming gene (PTTG) expression and phosphorylation in thyroid cells. in Endocrinology 2013
Human Polyclonal TGFA Primary Antibody for IHC, IHC (p) - ABIN4358876
Badawy, El-Hindawi, Hammam, Moussa, Gabal, Said: Impact of epidermal growth factor receptor and transforming growth factor-α on hepatitis C virus-induced hepatocarcinogenesis. in APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2015
TGFA TaqI polymorphism was not associated with the risk of nonsyndromic cleft lip and/or palate in Iranian children.
Results suggest a long non-coding RNA MALAT1/MIR376A/transforming growth factor alpha (TGFA) axis mediates osteosarcoma (OS) cell proliferation and tumor progression.
The association of the TGFA gene with NS-CL+/-P in Korean populations was not clearly found. However, the etiologic effect of the TGFA gene on NS-CL+/-P patients should be investigated in terms of maternal genotype influence.
There were no significant differences in GE area of infertile and fertile women. C-C motif chemokine 11 (P=0.048), TGFalpha (P=0.049), IFNgamma (P=0.033) and interleukin-1 alpha (show IL1A Antibodies) (P=0.047) were significantly elevated in uterine lavage from infertile women <35years compared to fertile but not in women 35years
results therefore demonstrate cancer epigenetics induces a loop of cancer-stroma-cancer interaction in omental microenvironment that promotes peritoneal metastasis of ovarian cancer cells via TNFalpha (show TNF Antibodies)-TGFalpha-EGFR (show EGFR Antibodies).
In conclusion, we identified four novel loci (TGFA, PIK3R1, FGFR3 (show FGFR3 Antibodies) and TREH (show TREH Antibodies)) and confirmed two loci known to be associated with cartilage thickness.The identified associations were not caused by rare exonic variants. This is the first report linking TGFA to human Osteoarthritis, which may serve as a new target for future therapies.
Our study showed that TGFA/TGFB3 (show TGFB3 Antibodies)/MSX1 (show MSX1 Antibodies) gene polymorphisms were associated with congenital NSHI. The distribution of genotype frequencies and allele frequencies of TGFA rs3771494, TGFB3 (show TGFB3 Antibodies) rs3917201 and rs2268626, and MSX1 (show MSX1 Antibodies) rs3821949 and rs62636562 were significantly different between the case and the control groups
TGFA gene expression is regulated by MiR (show MLXIP Antibodies)-374a in lung adenocarcinoma.TGFA plays role in lung adenocarcinoma cell proliferation and invasion.
Overall, our findings indicated that intratumoral administration of TGFalphaL3-SEB effectively inhibited the growth of breast tumors through induction of necrosis and suppressing proliferation and angiogenesis without systemic toxicity.
TGFA expression decreased after 10 and 30min of treatment even when transcription was not inhibited. We found that activation of PI3K (show PIK3CA Antibodies) was necessary for triiodothyronine to modulate HIF1A (show HIF1A Antibodies) and TGFA expression
upregulation of TGFalpha or FGF2 (show FGF2 Antibodies) expression is not a pre-requisite for enhanced testicular growth and increased Sertoli cell proliferation that occurs subsequent to hemicastration in the neonatal boar
Tgfa null mice are equally susceptible to spontaneous osteoarthritis development during aging.
Here the authors show that the mammalian rhomboid protease RHBDL4 (also known as Rhbdd1) promotes trafficking of several membrane proteins, including the EGFR (show EGFR Antibodies) ligand TGFalpha, from the endoplasmic reticulum (ER) to the Golgi apparatus, thereby triggering their secretion by extracellular microvesicles.
TGF-alpha contributes to the progression of diabetic kidney disease.
c-Myc (show MYC Antibodies) and transforming growth factor alpha enhance the development of hepatic lesions due to mutant beta-catenin (show CTNNB1 Antibodies) in transgenic mice.
Reverse transcriptase polymerase chain reaction studies showed that three members, Tgfa, Hbegf,and Nrg1 of the EGF family were expressed in the epithelium cultured with FGF7 + LPA as well as in the epithelium freshly isolated from the rudiments.
findings suggest that elevated PHD4 (show P4HTM Antibodies) levels disturb the angiogenic balance in osteosarcoma via induction of the TGF-alpha pathway and inhibit tumor growth by reducing the expression of HIF-2alpha (show EPAS1 Antibodies)
Interaction between IRF6 (show IRF6 Antibodies) and TGFA genes contribute to the risk of nonsyndromic cleft lip/palate.
These results imply that TGFalpha stimulates proliferation of endometrial stromal cells through multiple mechanisms, including its regulation of Igfbp3 (show IGFBP3 Antibodies) and Mmp3 (show MMP3 Antibodies) transcription.
ADAM-17 (show ADAM17 Antibodies) and TGF-alpha are strongly and locally upregulated following adult mice cortical damage.
Different mechanisms regulate neurogenesis in neonatal and adult olfactory epithelium; fibroblast growth factor (FGF)2 (show FGF2 Antibodies) and TGFalpha may have different roles throughout development.
This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, protransforming growth factor alpha
, transforming growth factor alpha
, transforming growth factor, alpha
, transforming growth factor-alpha
, waved 1
, TGF alpha