Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

NPC1 Antibodies

(Niemann-Pick Disease, Type C1 (NPC1))
This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain.
anti-Niemann-Pick Disease, Type C1 (NPC1) (AA 34-174) antibody anti-Niemann-Pick Disease, Type C1 (NPC1) (AA 34-174) antibody anti-Niemann-Pick Disease, Type C1 (NPC1) (AA 34-174) antibody [ABIN1724876]

NPC1 Reactivity: Human IHC, ELISA, WB Host: Mouse Monoclonal 8D10B6 unconjugated

anti-Niemann-Pick Disease, Type C1 (NPC1) (AA 34-174) antibody anti-Niemann-Pick Disease, Type C1 (NPC1) (AA 34-174) antibody anti-Niemann-Pick Disease, Type C1 (NPC1) (AA 34-174) antibody [ABIN1845969]

NPC1 Reactivity: Human FACS, IHC, ELISA, WB Host: Mouse Monoclonal unconjugated

anti-Niemann-Pick Disease, Type C1 (NPC1) (AA 591-620) antibody anti-Niemann-Pick Disease, Type C1 (NPC1) (AA 591-620) antibody anti-Niemann-Pick Disease, Type C1 (NPC1) (AA 591-620) antibody [ABIN3031998]

NPC1 Reactivity: Human IF, IHC, ELISA, WB Host: Rabbit Polyclonal unconjugated

NPC1 Antibodies by Grade

Find NPC1 Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

NPC1 Antibodies by Reactivity

Find NPC1 Antibodies for a variety of species such as anti-Human NPC1, anti-Mouse NPC1, anti-Rat NPC1. The species listed below are among those available. Click on a link to go to the corresponding products.

NPC1 Antibodies by Application

Find NPC1 Antibodies validated for a specific application such as ELISA, WB, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

NPC1 Antibodies by Host

Find NPC1 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

NPC1 Antibodies by Binding Specificity

Find NPC1 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

NPC1 Antibodies by Clonality

Find available monoclonal or polyclonal NPC1 Antibodies. Click on a link to go to the corresponding products.

NPC1 Antibodies by Clone

Find NPC1 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

NPC1 Antibodies by Conjugate

Find NPC1 Antibodies with a specific conjugate such as Biotin, FITC, PE. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular NPC1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, FM, IHC, WB
Validations
  • collections(3)
Cat. No. ABIN6655360
Quantity 100 μg
Reactivity Human
Application IF, IHC (p), WB
Validations
  • collections(3)
Cat. No. ABIN657395
Quantity 400 μL
Reactivity Human
Application IF, IHC, WB
Validations
  • collections(3)
Cat. No. ABIN2447143
Quantity 400 μL
Reactivity Human
Application ELISA, WB
Validations
  • collections(3)
Cat. No. ABIN562034
Quantity 100 μg
Reactivity Human
Application IF, IHC, IHC (p), IP, WB
Validations
  • collections(3)
Cat. No. ABIN462125
Quantity 50 μg
Reactivity Hamster, Human, Mouse
Application IF, IP, IHC, WB
Validations
  • collections(2)
Cat. No. ABIN363474
Quantity 0.1 mL
Reactivity Human
Application EIA, IHC (p), WB
Validations
  • collections(2)
Cat. No. ABIN500383
Quantity 0.1 mg
Reactivity
Application IEM, IF, IHC, IP, WB
Validations
  • (3)
  • collections(1)
Cat. No. ABIN540364
Quantity 100 μL
Reactivity Human
Application ELISA, WB
Validations
  • collections(1)
Cat. No. ABIN1590132
Quantity 100 μg
Reactivity Human, Mouse, Rat
Application ELISA, WB
Validations
  • collections(1)
Cat. No. ABIN5693129
Quantity 100 μg
Reactivity Human, Mouse, Rat
Application ELISA, WB
Validations
  • collections(1)
Cat. No. ABIN5708097
Quantity 100 μg
Reactivity Mouse
Application ELISA
Validations
Cat. No. ABIN570865
Quantity 100 μg
Reactivity Human
Application ELISA, IHC, WB
Validations
Cat. No. ABIN7161727
Quantity 100 μg
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7161728
Quantity 100 μg
Reactivity Human
Application
Validations
Cat. No. ABIN7161729
Quantity 100 μg

Latest Publications on our NPC1 Antibodies

Ferrante, De Nuccio, Pepponi, Visentin, Martire, Bernardo, Minghetti, Popoli: "Stimulation of adenosine A2A receptors reduces intracellular cholesterol accumulation and rescues mitochondrial abnormalities in human neural cell models of Niemann-Pick C1." in: Neuropharmacology, Vol. 103, pp. 155-62, (2016) (PubMed).

Ebrahimi-Fakhari, Wahlster, Bartz, Werenbeck-Ueding, Praggastis, Zhang, Joggerst-Thomalla, Theiss, Grimm, Ory, Runz: "Reduction of TMEM97 increases NPC1 protein levels and restores cholesterol trafficking in Niemann-pick type C1 disease cells." in: Human molecular genetics, (2016) (PubMed).

Li, Deffieu, Lee, Saha, Pfeffer: "Glycosylation inhibition reduces cholesterol accumulation in NPC1 protein-deficient cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 48, pp. 14876-81, (2015) (PubMed).

Armstrong, Mattsson, Appelqvist, Janefjord, Sandin, Agholme, Olsson, Svensson, Blennow, Zetterberg, Kågedal: "Lysosomal network proteins as potential novel CSF biomarkers for Alzheimer's disease." in: Neuromolecular medicine, Vol. 16, Issue 1, pp. 150-60, (2014) (PubMed).

Zampieri, Bembi, Rosso, Filocamo, Dardis: "Treatment of Human Fibroblasts Carrying NPC1 Missense Mutations with MG132 Leads to an Improvement of Intracellular Cholesterol Trafficking." in: JIMD reports, Vol. 2, pp. 59-69, (2013) (PubMed).

Ohgane, Karaki, Dodo, Hashimoto: "Discovery of oxysterol-derived pharmacological chaperones for NPC1: implication for the existence of second sterol-binding site." in: Chemistry & biology, Vol. 20, Issue 3, pp. 391-402, (2013) (PubMed).

Fu, Wassif, Yanjanin, Watkins-Chow, Baxter, Incao, Liscum, Sidhu, Firnkes, Graham, Ory, Porter, Pavan: "Efficacy of N-acetylcysteine in phenotypic suppression of mouse models of Niemann-Pick disease, type C1." in: Human molecular genetics, Vol. 22, Issue 17, pp. 3508-23, (2013) (PubMed).

Roszell, Tao, Yu, Gao, Huang, Ning, Feinstein, Vite, Bates: "Pulmonary abnormalities in animal models due to Niemann-Pick type C1 (NPC1) or C2 (NPC2) disease." in: PLoS ONE, Vol. 8, Issue 7, pp. e67084, (2013) (PubMed).

Cianciola, Greene, Morton, Carlin: "Adenovirus RIDα uncovers a novel pathway requiring ORP1L for lipid droplet formation independent of NPC1." in: Molecular biology of the cell, Vol. 24, Issue 21, pp. 3309-25, (2013) (PubMed).

Kanerva, Uronen, Blom, Li, Bittman, Lappalainen, Peränen, Raposo, Ikonen: "LDL cholesterol recycles to the plasma membrane via a Rab8a-Myosin5b-actin-dependent membrane transport route." in: Developmental cell, Vol. 27, Issue 3, pp. 249-62, (2013) (PubMed).

Aliases for NPC1 Antibodies

NPC intracellular cholesterol transporter 1 (NPC1) Antibodies
Niemann-Pick disease, type C1 (npc1) Antibodies
Niemann-Pick C1 protein (LOC579887) Antibodies
NPC intracellular cholesterol transporter 1 (Npc1) Antibodies
A430089E03Rik Antibodies
C85354 Antibodies
Cdig2 Antibodies
D18Ertd139e Antibodies
D18Ertd723e Antibodies
im:7149020 Antibodies
lcsd Antibodies
nmf164 Antibodies
NPC Antibodies
spm Antibodies
wu:fb53a12 Antibodies
wu:fc29a12 Antibodies
You are here:
help Support