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anti-Mouse (Murine) ESRRB Antibodies:
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Human Polyclonal ESRRB Primary Antibody for FACS, IHC (p) - ABIN653004
Chang, Park, Ahn, Nam, Jung, Park, Lee, Balch, Powis, Ku, Kim: Improving gastric cancer preclinical studies using diverse in vitro and in vivo model systems. in BMC cancer 2016
Cow (Bovine) Polyclonal ESRRB Primary Antibody for IHC (p) - ABIN4309542
Real, Heredia, Dávila, Guirado: Efferent retinal projections visualized by immunohistochemical detection of the estrogen-related receptor beta in the postnatal and adult mouse brain. in Neuroscience letters 2008
Human Polyclonal ESRRB Primary Antibody for ICC, IF - ABIN446264
Xu, Ang, Sevilla, Lemischka, Maayan: Construction and validation of a regulatory network for pluripotency and self-renewal of mouse embryonic stem cells. in PLoS computational biology 2014
The resulting cells express the components of the core transcriptional network of mESCs, including ESRRB, at high levels, which suggests the existence of naive-state hiPSCs that are similar to mESCs. We also demonstrate that these cells differentiate more readily into neural cells than do conventional hiPSCs.
When transduced with Oct4, Sox2, and Klf4 (OSK) into murine fibroblasts, Zic3 and Esrrb synergistically enhance the reprogramming efficiency by regulating cellular metabolic pathways.
Taken together these observations suggest that ESRRbeta is a critical component in the onset of Ddilated cardiomyopathy by affecting contractility and calcium balance
Findings indicate that the Gata6 promoter is activated by Esrrb in association with Ncoa3, and Dax1 inhibited activities of Esrrb and Ncoa3, resulting maintenance of the undifferentiated status of embryonic stem (ES) cells.
mitotic Esrrb binding is highly dynamic, driven by specific recognition of its DNA-binding motif and is associated with early transcriptional activation of target genes after completion of mitosis
JARID2 physically interacts with ESRRB, SALL4A, and PRDM14
interacts in trophoblast stem cells with the histone demethylase Lsd1 and with the RNA Polymerase II-associated Integrator complex
The forced expression of Essrb (and Nanog) resulted in the dispensability of nucleostemin expression in embryonic stem cells.
Daily regulation of Esrrb in photoreceptor cells may contribute to their adaptation to 24-h changes in metabolic demands.
Loss of Errbeta affects body composition, neuropeptide levels, stress hormones, and centrally-modulated startle responses of mice.
Esrrb selective deletion in the hindbrain alters neuropeptide Y expression, whole-body energy level and ingestive behavior.
Esrrb forms a heterodimer complex with Sox2 in ES cells to regulate transcriptional differences between mouse embryonic and epiblast stem cells.
Dax1 functions as a negative regulator of Esrrb and Oct3/4, and these molecules form a regulatory loop for controlling the pluripotency and self-renewal capacity of embryonic stem cells.
a direct Nanog target gene that can substitute for Nanog function in pluripotent cell
a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal
we present evidence that chondrolectin (Chodl) is expressed by fast motor neurons and that estrogen-related receptor beta (ERRbeta) is a candidate marker for slow motor neurons in the spinal cord
ERRbeta is a critical regulator of rod photoreceptor function and survival
Data demonstrate that estrogen-related receptor (ERR) beta is transiently induced, and ERRgamma is dramatically induced (and accumulates) in a differentiation-dependent manner in skeletal muscle cells.
estrogen receptor beta knockout females exhibit lordosis behaviour equal to that of wild-type females
the calcium level was associated with genetic variations in AMELX, AMNB and ESRRB. AMELX and AMNB are involved in enamel mineralization. Mutations in both these genes are responsible for the amelogenesis imperfecta phenotype (OMIN), which supports their link with enamel alterations as well as enamel mineralization.
SNP (rs61742642; C to T, P386S) in the ligand-binding domain of human estrogen-related receptor beta is associated with audiometric temporary threshold shift.
ESRRbeta is mislocalized in human myocardium samples with idiopathic dilated cardiomyopathy, suggesting a possible role for ESRRbeta in the pathogenesis of idiopathic dilated cardiomyopathy in humans
The rs1676303 TT (P=0.02) and rs6574293 GG (P=0.04) genotypes of ESRRB were associated with RCD and TMD, respectively.
analysis of Esrrb target genes indicates Esrrb may be an important factor in regulating cell proliferation
ERRbeta has a role in estrogen-dependent cellular function including cancer cell proliferation
The significant association and the presence of high-risk haplotypes identified in the ESRRB gene confirm the association of variants in ESRRB and rotator cuff disease.
study concludes ESRRB, a gene when mutated causes a form of hearing impairment, also contributes to dental decay likely by influencing the formation of an enamel surface more susceptible to demineralization under acidic conditions
ERRbeta signalling leads to BCAS2-mediated blockage of the G1/S transition and inhibition of the epithelial to mesenchymal transition through FST-mediated regulation of E-cadherin
This is the first report of DFNB35 mutations in the Czech Republic and it seems to be a rare cause of non-syndromic hearing loss.
A novel missense mutation in the ESRRB gene causes DFNB35 hearing loss in a Tunisian family.
Data confirm the up-regulation of ER-beta as the principal receptor involved in the progression of human endometriosis.
Parkin degrades ESRRA, ESRRB and ESRRG to limit the expression of MAOA and MAOB.
Data show that variant isoforms of estrogen receptor related beta protein have differential effects on ER alpha-dependent gene expression, and possibly on endometrial cell function.
ERRs, which are coexpressed with ERs in prostatic cells, could regulate cell growth and modulate ER-mediated pathways via interference on ERalpha transcription in prostatic cells.
ERRbeta plays a repressor role in the Nrf2-ARE pathway
ERRbeta performs a tumor suppressing function in prostate cancer cells.
Sequence analysis of the ESRRB gene in the affected individuals of the original DFNB35 family and in three other DFNB35-linked consanguineous families from Pakistan revealed four missense mutations.
Receptor estrogen-related receptors alpha, beta and gamma physically interact with HIF and stimulate HIF-induced transcription in tumor cells cultured under hypoxia.
ESRRB is a crucial transcription factor to improve the self-renewal of porcine induced pluripotent stem cells.
ERbeta is expressed in the cotyledon of the placenta and suggest a role of ER beta primarily in trophoblast cell differentiation and placental angiogenesis and/or vascular functions.
This gene encodes a protein with similarity to the estrogen receptor. Its function is unknown; however, a similar protein in mouse plays an essential role in placental development.
, estrogen-related receptor beta
, steroid hormone receptor ERR2-like
, estrogen receptor related 2
, estrogen receptor-like 2
, nuclear receptor subfamily 3 group B member 2
, steroid hormone receptor ERR2
, ERR beta-2
, estrogen-related nuclear receptor beta
, nuclear receptor ERRB2
, orphan nuclear receptor
, estrogen-related receptor, beta