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Human Polyclonal ESRRB Primary Antibody for ICC, IF - ABIN446264
Xu, Ang, Sevilla, Lemischka, Maayan: Construction and validation of a regulatory network for pluripotency and self-renewal of mouse embryonic stem cells. in PLoS computational biology 2014
Cow (Bovine) Polyclonal ESRRB Primary Antibody for IHC (p) - ABIN4309542
Real, Heredia, Dávila, Guirado: Efferent retinal projections visualized by immunohistochemical detection of the estrogen-related receptor beta in the postnatal and adult mouse brain. in Neuroscience letters 2008
When transduced with Oct4 (show POU5F1 Antibodies), Sox2 (show SOX2 Antibodies), and Klf4 (show KLF4 Antibodies) (OSK) into murine fibroblasts, Zic3 (show ZIC3 Antibodies) and Esrrb synergistically enhance the reprogramming efficiency by regulating cellular metabolic pathways.
Findings indicate that the Gata6 (show GATA6 Antibodies) promoter is activated by Esrrb in association with Ncoa3 (show NCOA3 Antibodies), and Dax1 (show NR0B1 Antibodies) inhibited activities of Esrrb and Ncoa3 (show NCOA3 Antibodies), resulting maintenance of the undifferentiated status of embryonic stem (ES) cells.
mitotic Esrrb binding is highly dynamic, driven by specific recognition of its DNA-binding motif and is associated with early transcriptional activation of target genes after completion of mitosis
JARID2 (show JARID2 Antibodies) physically interacts with ESRRB, SALL4A (show SALL4 Antibodies), and PRDM14 (show PRDM14 Antibodies)
interacts in trophoblast stem cells with the histone demethylase Lsd1 and with the RNA Polymerase II-associated Integrator complex
The forced expression of Essrb (and Nanog (show NANOG Antibodies)) resulted in the dispensability of nucleostemin (show E2IG3 Antibodies) expression in embryonic stem cells.
Daily regulation of Esrrb in photoreceptor cells may contribute to their adaptation to 24-h changes in metabolic demands.
Loss of Errbeta affects body composition, neuropeptide levels, stress hormones, and centrally-modulated startle responses of mice.
Esrrb selective deletion in the hindbrain alters neuropeptide Y (show NPY Antibodies) expression, whole-body energy level and ingestive behavior.
Esrrb forms a heterodimer complex with Sox2 (show SOX2 Antibodies) in ES cells to regulate transcriptional differences between mouse embryonic and epiblast stem cells.
the calcium level was associated with genetic variations in AMELX (show AMELX Antibodies), AMNB and ESRRB. AMELX (show AMELX Antibodies) and AMNB are involved in enamel mineralization. Mutations in both these genes are responsible for the amelogenesis imperfecta phenotype (OMIN), which supports their link with enamel alterations as well as enamel mineralization.
SNP (rs61742642; C to T, P386S) in the ligand-binding domain of human estrogen-related receptor beta is associated with audiometric temporary threshold shift.
The rs1676303 TT (P=0.02) and rs6574293 GG (P=0.04) genotypes of ESRRB were associated with RCD (show BCL10 Antibodies) and TMD (show TTN Antibodies), respectively.
analysis of Esrrb target genes indicates Esrrb may be an important factor in regulating cell proliferation
ERRbeta has a role in estrogen-dependent cellular function including cancer cell proliferation
The significant association and the presence of high-risk haplotypes identified in the ESRRB gene confirm the association of variants in ESRRB and rotator cuff (show CUFF Antibodies) disease.
study concludes ESRRB, a gene when mutated causes a form of hearing impairment, also contributes to dental decay likely by influencing the formation of an enamel surface more susceptible to demineralization under acidic conditions
ERRbeta signalling leads to BCAS2 (show BCAS2 Antibodies)-mediated blockage of the G1/S transition and inhibition of the epithelial to mesenchymal transition through FST (show FST Antibodies)-mediated regulation of E-cadherin (show CDH1 Antibodies)
This is the first report of DFNB35 mutations in the Czech Republic and it seems to be a rare cause of non-syndromic hearing loss.
A novel missense mutation in the ESRRB gene causes DFNB35 hearing loss in a Tunisian family.
ESRRB is a crucial transcription factor to improve the self-renewal of porcine induced pluripotent stem cells.
ERbeta (show ESR2 Antibodies) is expressed in the cotyledon of the placenta and suggest a role of ER beta (show ESR2 Antibodies) primarily in trophoblast cell differentiation and placental angiogenesis and/or vascular functions.
This gene encodes a protein with similarity to the estrogen receptor. Its function is unknown; however, a similar protein in mouse plays an essential role in placental development.
, estrogen-related receptor beta
, steroid hormone receptor ERR2-like
, estrogen receptor related 2
, estrogen receptor-like 2
, nuclear receptor subfamily 3 group B member 2
, steroid hormone receptor ERR2
, ERR beta-2
, estrogen-related nuclear receptor beta
, nuclear receptor ERRB2
, orphan nuclear receptor
, estrogen-related receptor, beta