Browse our anti-Exocyst Complex Component 4 (EXOC4) Antibodies

Full name:: anti-Exocyst Complex Component 4 Antibodies (EXOC4)

On www.antibodies-online.com are 30 Exocyst Complex Component 4 (EXOC4) Antibodies from 12 different suppliers available. Additionally we are shipping Exocyst Complex Component 4 Proteins (4) and many more products for this protein. A total of 40 Exocyst Complex Component 4 products are currently listed.

Synonyms:: ALR, ATSEC8, C78892, CG2095, DKFZp459N1430, Dmel\\CG2095, dsec8, fun, SEC8, Sec8l1, Sec8p, si:ch211-92l17.2, si:rp71-18a24.2, subunit of exocyst complex 8

list all antibodies	Gene Name	GeneID	UniProt
	EXOC4	60412	Q96A65
	EXOC4	20336	O35382
	EXOC4	116654	Q62824
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Most Popular Reactivities for anti-Exocyst Complex Component 4 (EXOC4) Antibodies

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anti-Human Antibodies:

anti-Mouse (Murine) Antibodies:

17 WB Antibodies

anti-Rat (Rattus) Antibodies:

18 WB Antibodies

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Top referenced anti-Exocyst Complex Component 4 Antibodies

Human Monoclonal EXOC4 Primary Antibody for ELISA, WB - ABIN528409 : Imai, Yoshie, Haga-Tsujimura, Nashida, Shimomura: Exocyst subunits are involved in isoproterenol-induced amylase release from rat parotid acinar cells. in European journal of oral sciences 2012 (PubMed)
Human Polyclonal EXOC4 Primary Antibody for ICC, IF - ABIN4352426 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

More Antibodies against Exocyst Complex Component 4 Interaction Partners

Fruit Fly (Drosophila melanogaster) Exocyst Complex Component 4 (EXOC4) interaction partners

Sec5 (show EXOC2 Antibodies), Sec6 (show EXOC3 Antibodies) and Sec8 act as a complex, each member dependent on the others for proper localization and function
No evidence that Sec8 is required for basal neurotransmission, though glutamate (show GRIN2A Antibodies) receptor trafficking was mildly disrupted in sec8 mutants.

Human Exocyst Complex Component 4 (EXOC4) interaction partners

Sec8 regulates N-cadherin (show CDH2 Antibodies) expression by controlling Smad3 (show SMAD3 Antibodies) and Smad4 (show SMAD4 Antibodies) expression through CBP (show CREBBP Antibodies), thereby mediating the epithelial-mesenchymal transition.
Sec8 regulate Bcl-2 (show BCL2 Antibodies) and Mcl-1 (show MCL1 Antibodies) expressions but not Bcl-xl (show BCL2L1 Antibodies) in malignant peripheral nerve sheath tumor cells.
Sec8 regulates histone-modifying proteins ATF2 (show ATF2 Antibodies) and RNF20 (show RNF20 Antibodies).
Sec8 knockdown in HSC3 cells resulted in reduced expressions of PAK1 (show PAK1 Antibodies) and PAK2 (show PAK2 Antibodies) by upregulating Pirh2 (show RCHY1 Antibodies) and Siah1 (show SIAH1 Antibodies) expression, which inhibited the ERK (show EPHB2 Antibodies) or p38 MAPK (show MAPK14 Antibodies) signalling pathway and cytokeratin8 phosphorylation and cell migration.
knockdown of Sec8 enhances the binding of JIP4 (show SPAG9 Antibodies) to MAPK (show MAPK1 Antibodies) kinase 4, thereby decreasing the phosphorylation of MAPK (show MAPK1 Antibodies) kinase 4, JNK (show MAPK8 Antibodies), and p38 (show CRK Antibodies).
Exome sequencing revealed a likely pathogenic mutation in three novel candidate MKS (show MKS1 Antibodies) disease genes-C5orf42 (show C5ORF42 Antibodies), EVC2 (show EVC2 Antibodies) and SEC8 (also known as EXOC4), which encodes an exocyst protein with an established role in ciliogenesis
High Sec8 expression is associated with progression of oral squamous-cell carcinoma by secretion of matrix metalloproteinases.
EXOC4 is involved in insulin (show INS Antibodies)-stimulated glucose transport and may be a candidate for an association with type 2 diabetes.
The exocyst subunits Sec3 (show EXOC1 Antibodies) and Sec8 interact with the polarity protein IQGAP1 (show IQGAP1 Antibodies) and that this interaction is triggered by active Cdc42 (show CDC42 Antibodies) and RhoA (show RHOA Antibodies), which are essential for matrix degradation.

Mouse (Murine) Exocyst Complex Component 4 (EXOC4) interaction partners

CREG1 (show CREG1 Antibodies) interacts with Sec8 to promote cardiomyogenic differentiation and cell-cell adhesion.
SAP102 (show DLG3 Antibodies) interacts with the PDZ (show INADL Antibodies)-binding domain of Sec8, a member of the exocyst complex. Interactions between the two proteins are involved in the delivery of N-methyl-D-aspartate receptors to the cell surface in heterologous cells and neurons.
the exocyst complex serves to selectively regulate the docking of insulin (show INS Antibodies)-containing vesicles at sites of release close to the plasma membrane
Sec8 controls the directional movement of AMPA (show GRIA3 Antibodies) receptors towards synapses through PDZ (show INADL Antibodies)-dependent interactions.
Insulin (show INS Antibodies) stimulates the phosphorylation of the exocyst protein Sec8 in adipocytes.
Interaction of Discs large 1 (Dlg1 (show DLG4 Antibodies)) with the Sec8 exocyst component promotes membrane addition, whereas with myotubularin-related protein 2 (Mtmr2 (show MTMR2 Antibodies)), negatively regulates membrane formation.

Arabidopsis thaliana Exocyst Complex Component 4 (EXOC4) interaction partners

The amount of pectinaceous mucilage and seed coat structure in sec8 and exo70A1 exocyst mutants, was characterized.
An allelic series of six independent T-DNA mutations reveal a role for SEC8 in male gametophyte function.
SEC8 copurifies in a high molecular mass fraction of 900 kD, interacts with SEC6 (show EXOC3 Antibodies), and functions as a subunit in a exocyst complex that plays important roles in morphogenesis.

Exocyst Complex Component 4 (EXOC4) Antigen Profile

Antigen Summary

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with Exocyst Complex Component 4 (EXOC4)

Secretory 8 (Sec8) antibody
exocyst complex component 4 (EXOC4) antibody
exocyst complex component 4 (CpipJ_CPIJ001354) antibody
exocyst complex component 4 (Exoc4) antibody
exocyst complex component 4 (exoc4) antibody
exocyst complex component 4 L homeolog (exoc4.L) antibody
Exocyst complex component 4 (sec-8) antibody
subunit of exocyst complex 8 (SEC8) antibody

ALR antibody
ATSEC8 antibody
C78892 antibody
CG2095 antibody
DKFZp459N1430 antibody
Dmel\\CG2095 antibody
dsec8 antibody
fun antibody
SEC8 antibody
Sec8l1 antibody
Sec8p antibody
si:ch211-92l17.2 antibody
si:rp71-18a24.2 antibody
subunit of exocyst complex 8 antibody

Protein level used designations for EXOC4

CG2095-PA , funnel cakes , sec8-PA , SEC8 protein , exocyst complex component 4 , SEC8-like 1 , exocyst complex component Sec8 , augmenter of liver regeneration (ALR) pseudogene , rSec8 , secretory protein SEC8

GENE ID	SPECIES
40712	Drosophila melanogaster
463740	Pan troglodytes
482250	Canis lupus familiaris
6032553	Culex quinquefasciatus
100065209	Equus caballus
100171903	Pongo abelii
100583695	Nomascus leucogenys
60412	Homo sapiens
20336	Mus musculus
116654	Rattus norvegicus
559866	Danio rerio
779032	Xenopus laevis
416700	Gallus gallus
537690	Bos taurus
172924	Caenorhabditis elegans
820201	Arabidopsis thaliana

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