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HEN1 Methyltransferase Homolog 1 (HENMT1) (C-Term) Peptide

HENMT1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN2184616
  • Target See all HENMT1 products
    HENMT1 (HEN1 Methyltransferase Homolog 1 (HENMT1))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    QVESLRVSHL PRRKEQAGER GDKPKDIGGS KAPVPCFGPV FTEVEKAKIE
    Characteristics
    This is a synthetic peptide designed for use in combination with antiHENMT1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at 20C. Avoid repeat freezethaw cycles.
  • Target
    HENMT1 (HEN1 Methyltransferase Homolog 1 (HENMT1))
    Background
    HENMT1 is a methyltransferase that adds a 2'Omethyl group at the 3'end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicerindependent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.

    Alias Symbols: C1orf59, HEN1

    Protein Size: 393
    Molecular Weight
    44 kDa
    Gene ID
    113802
    NCBI Accession
    NM_144584, NP_653185
    UniProt
    Q5T8I9
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