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Transcription Factor B1, Mitochondrial (TFB1M) (C-Term) Peptide

TFB1M Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5511607

Quick Overview for Transcription Factor B1, Mitochondrial (TFB1M) (C-Term) Peptide (ABIN5511607)

Target

TFB1M (Transcription Factor B1, Mitochondrial (TFB1M))

Origin

Human

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequence

    SISHFKSLCD VYRKMCDEDP QLFAYNFREE LKRRKSKNEE KEEDDAENYR

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-TFB1M Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    TFB1M (Transcription Factor B1, Mitochondrial (TFB1M))

    Background

    The protein encoded by this gene is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. The encoded protein also is part of the basal mitochondrial transcription complex and is necessary for mitochondrial gene expression. The methylation and transcriptional activities of this protein are independent of one another. Variations in this gene may influence the severity of aminoglycoside-induced deafness (AID).

    Alias Symbols: CGI75, mtTFB, CGI-75, mtTFB1

    Protein Size: 346

    Gene ID

    51106

    NCBI Accession

    NM_016020, NP_057104

    UniProt

    Q8WVM0
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