Transcription Factor B1, Mitochondrial (TFB1M) (C-Term) Peptide
TFB1M
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TFB1M products
- TFB1M (Transcription Factor B1, Mitochondrial (TFB1M))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SISHFKSLCD VYRKMCDEDP QLFAYNFREE LKRRKSKNEE KEEDDAENYR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TFB1M Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TFB1M (Transcription Factor B1, Mitochondrial (TFB1M))
- Background
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The protein encoded by this gene is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. The encoded protein also is part of the basal mitochondrial transcription complex and is necessary for mitochondrial gene expression. The methylation and transcriptional activities of this protein are independent of one another. Variations in this gene may influence the severity of aminoglycoside-induced deafness (AID).
Alias Symbols: CGI75, mtTFB, CGI-75, mtTFB1
Protein Size: 346 - Gene ID
- 51106
- NCBI Accession
- NM_016020, NP_057104
- UniProt
- Q8WVM0
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