Transcription Factor E3 (TFE3) (Middle Region) Peptide
TFE3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TFE3 products
- TFE3 (Transcription Factor E3 (TFE3))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- IRKLQKEQQR SKDLESRQRS LEQANRSLQL RIQELELQAQ IHGLPVPPTP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TFE3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Transcription Factor E3 (TFE3) peptide
TFE3 Reactivity: Human, Cow, Dog, Mouse Host: Synthetic BP, Imm
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TFE3 (Transcription Factor E3 (TFE3))
- Background
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This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants.
Alias Symbols: TFEA, RCCP2, RCCX1, bHLHe33
Protein Size: 575 - Gene ID
- 7030
- NCBI Accession
- NM_001282142, NP_001269071
- UniProt
- P19532
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