Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (C-Term) Peptide
PICK1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511940
Quick Overview for Protein Interacting With Protein Kinase C, alpha 1 (PICK1) (C-Term) Peptide (ABIN5511940)
Target
PICK1
(Protein Interacting With Protein Kinase C, alpha 1 (PICK1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- FPIEVDLAHT TLAYGLNQEE FTDGEEEEEE EDTAAGEPSR DTRGAAGPLD
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PICK1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))
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Background
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The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene.
Alias Symbols: PICK1,PRKCABP,
Protein Size: 415 -
Gene ID
- 9463
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NCBI Accession
- NP_036539
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UniProt
- Q9NRD5
Target
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