Histamine N-Methyltransferase (HNMT) (Middle Region) Peptide
HNMT
Reactivity: Human
Host: Synthetic
BP, WB
-
- Target See all HNMT products
- HNMT (Histamine N-Methyltransferase (HNMT))
- Protein Region
- Middle Region
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- STMDISDCFI DGNENGDLLW DFLTETCNFN ATAPPDLRAE LGKDLQEPEF
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- HNMT Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- HNMT (Histamine N-Methyltransferase (HNMT))
- Background
-
In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
Alias Symbols: HMT, HNMT-S1, HNMT-S2
Protein Size: 292 - Gene ID
- 3176
- NCBI Accession
- NM_001024074, NP_001019245
- UniProt
- P50135
-
You are here:
