Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (C-Term) Peptide
MAP3K7
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512406
Quick Overview for Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (C-Term) Peptide (ABIN5512406)
Target
MAP3K7
(Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- VTGTEPGQVS SRSSSPSVRM ITTSGPTSEK PTRSHPWTPD DSTDTNGSDN
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MAP3K7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
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Background
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The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2, this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: MAP3K7, TAK1,
Protein Size: 579 -
Gene ID
- 6885
Target
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