Retinol Dehydrogenase 5 (11-Cis/9-Cis) (RDH5) (Middle Region) Peptide
RDH5
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5512524
Quick Overview for Retinol Dehydrogenase 5 (11-Cis/9-Cis) (RDH5) (Middle Region) Peptide (ABIN5512524)
Target
RDH5
(Retinol Dehydrogenase 5 (11-Cis/9-Cis) (RDH5))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- RGFRVLASCL TPSGAEDLQR VASSRLHTTL LDITDPQSVQ QAAKWVEMHV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- RDH5 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RDH5 (Retinol Dehydrogenase 5 (11-Cis/9-Cis) (RDH5))
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Background
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This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene.
Alias Symbols: RDH1, 9cRDH, SDR9C5, HSD17B9
Protein Size: 318 -
Gene ID
- 5959
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NCBI Accession
- NM_001199771, NP_001186700
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UniProt
- Q92781
Target
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