Tropomyosin 1 (Alpha) (TPM1) (N-Term) Peptide
TPM1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Tropomyosin (TPM1) products
- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DAEADVASLN RRIQLVEEEL DRAQERLATA LQKLEEAEKA ADESERGMKV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TPM1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
- Background
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This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.
Alias Symbols: TPM1,C15orf13,TMSA,
Protein Size: 284 - Gene ID
- 7168
- NCBI Accession
- XP_006720731
- UniProt
- P09493
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