Tropomyosin 1 (Alpha) (TPM1) Peptide
TPM1
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all Tropomyosin (TPM1) products
- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TPM1 antibody (Catalog #: ARP41392_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
- Synonyms
- alpha-fTM Peptide, Tm7 Peptide, tpm1 Peptide, MGC84844 Peptide, AA986836 Peptide, AI854628 Peptide, TM2 Peptide, Tm3 Peptide, Tmpa Peptide, Tpm-1 Peptide, alpha-TM Peptide, Alpha-tm Peptide, Tma2 Peptide, Tmsa Peptide, TPM1 Peptide, fb37a09 Peptide, tm Peptide, wu:fb37a09 Peptide, CH1 Peptide, alpha-tm Peptide, alpha-tropomyosin Peptide, C15orf13 Peptide, CMD1Y Peptide, CMH3 Peptide, HTM-alpha Peptide, TMSA Peptide, TPMA Peptide, Tm1 Peptide, zgc:171719 Peptide, zgc:55951 Peptide, zgc:77009 Peptide, tropomyosin 1 (alpha) Peptide, tropomyosin Peptide, tropomyosin 1 Peptide, tropomyosin 1, alpha Peptide, alpha-tropomyosin Peptide, tropomyosin 1 L homeolog Peptide, TPM1 Peptide, tm7 Peptide, Tpm1 Peptide, tpma Peptide, tpm1.L Peptide, Smp_044010.2 Peptide, LOC732984 Peptide, tpm1 Peptide
- Background
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TPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction.This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.
Alias Symbols: CMH3, TMSA, TPM1-alpha, CMD1Y, C15orf13, HTM-alpha
Protein Interaction Partner: ACTB,C19orf50,EPB41,JUN,PKD2,S100A2,TMOD2,TNNT1,TNNT2,TPM2,C19orf50,CNN1,TNNT1,TNNT2,TPM1,TPM2
Protein Size: 284 - Molecular Weight
- 31 kDa
- Gene ID
- 7168
- NCBI Accession
- NM_000366, NP_000357
- UniProt
- P09493
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