Coenzyme Q3, Methyltransferase (COQ3) (Middle Region) Peptide
COQ3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all COQ3 products
- COQ3 (Coenzyme Q3, Methyltransferase (COQ3))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- CGGGLLTEPL GRLGASVIGI DPVDENIKTA QCHKSFDPVL DKRIEYRVCS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-COQ3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- COQ3 (Coenzyme Q3, Methyltransferase (COQ3))
- Background
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Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.
Alias Symbols: COQ3,UG0215E05,
Protein Size: 369 - Gene ID
- 51805
- NCBI Accession
- NP_059117
- UniProt
- Q9NZJ6
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