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Parathyroid Hormone (PTH) (AA 4-13) Peptide

PTH Host: Synthetic
Rockland
Catalog No. ABIN6699483
Supplier Product No.: 000-001-m29
  • Target See all PTH products
    PTH (Parathyroid Hormone (PTH))
    Protein Region
    AA 4-13
    Source
    • 19
    Synthetic
    Supplier Product No.
    000-001-m29
    Supplier
    Rockland
    Purpose
    Parathyroid hormone (pTH) Rat 4-13 Peptide
    Purity
    Greater than 95% specific peptide.
  • Application Notes

    Other: Control peptide should be used at 1.0 μg per 1.0 μL of antiserum per assay.

    Application_Note: Parathyroid hormone (pTH) Rat 4-13 Control Peptide is suitable for use in ELISA, Western Blot, Dot blot, PCA, and other assays. Control peptide should be used at 1.0 μg per 1.0 μL of antiserum in per assay. Specific conditions for reactivity should be optimized by the end user.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution

    Reconstitution_Buffer: Restore with deionized water (or equivalent)

    Reconstitution_Volume: 1.0 mL

    Concentration
    1.0 mg/mL
    Storage
    4 °C,-20 °C
    Storage Comment
    Store vial at 2 - 8 ° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.
    Expiry Date
    12 months
  • Target
    PTH (Parathyroid Hormone (PTH))
    Target Type
    Hormone
    Background

    Synonyms: Parathyroid hormone, PTH, Parathormone, Parathyrin, control peptide, blocking peptide

    Background: Parathyroid hormone (pTH) is the most important endocrine regulator of Ca2+ and phosphorus concentration in the extracellular fluid. pTH is secreted from cells of the parathyroid glands and acts for the most part via the binding to specific G-protein coupled receptors on the surface of  target cells in bone and kidney, utilizing the second messenger adenylate cyclase to regulate cAMP levels in cells.  Like most other protein hormones, parathyroid hormone is synthesized as a preprohormone and is processed intracellularly.  The mature hormone, 84 amino acids in length, is released from secretory vesicles into the blood.  Biologic effects of large C-terminal parathyroid hormone (PTH) fragments, such as pTH 7-84, are thought to regulate PTH secretion via an autocrine/paracrine regulatory mechanism

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