Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) Peptide
P4HB
Reactivity: Mammalian
Host: Synthetic
BP, IHC, WB
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- Target See all P4HB products
- P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Sequence
- DRTVIDYNGE RTLDGFKKFL ESGGQDGAGD DDDLEDLEEA EEPDMEEDDD
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of P4 HB antibody,
Alternative Names: P4HB control peptide, P4HB antibody Blocking Peptide, Anti-P4HB Blocking Peptide, Procollagen-Proline 2-Oxoglutarate 4-Dioxygenase Beta Polypeptide Blocking Peptide, DSI Blocking Peptide, ERBA2L Blocking Peptide, GIT Blocking Peptide, PDI Blocking Peptide, PDIA1 Blocking Peptide, PHDB Blocking Peptide, PO4DB Blocking Peptide, PO4HB Blocking Peptide, PROHB Blocking Peptide, P4HB, PHB-4, PHB 4, PHB-4 Blocking Peptide, PHB 4 Blocking Peptide - Purification
- Purified
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
- Background
- P4HB is the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.
- Molecular Weight
- 55 kDa
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