Growth Hormone Secretagogue Receptor (GHSR) (C-Term) Peptide
GHSR
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all GHSR products
- GHSR (Growth Hormone Secretagogue Receptor (GHSR))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- AAINPILYNI MSKKYRVAVF RLLGFEPFSQ RKLSTLKDES SRAWTESSIN
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GHSR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GHSR (Growth Hormone Secretagogue Receptor (GHSR))
- Background
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This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein, this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin, however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.
Alias Symbols: -
Protein Interaction Partner: CORT,GHRL
Protein Size: 366 - Molecular Weight
- 40 kDa
- Gene ID
- 2693
- NCBI Accession
- NM_198407, NP_940799
- UniProt
- B3SXS8
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