Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A) Peptide
LRRC8A
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN979603
Quick Overview for Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A) Peptide (ABIN979603)
Target
LRRC8A
(Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-LRRC8A antibody (Catalog #: ARP49452_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))
-
Background
-
LRRC8A is a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. LRRC8A is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
Alias Symbols: FLJ10337, KIAA1437, LRRC8, AGM5
Protein Size: 810 -
Molecular Weight
- 94 kDa
-
Gene ID
- 56262
-
NCBI Accession
- NM_019594, NP_062540
-
UniProt
- Q8IWT6
Target
-
You are here:
