Transcription Factor MafK (MAFK) (N-Term) Peptide
MAFK
Reactivity: Mouse
Host: Synthetic
BP, WB
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- Target See all MAFK products
- MAFK (Transcription Factor MafK (MAFK))
- Protein Region
- N-Term
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- TTNPKPNKAL KVKKEAGENA PVLSDDELVS MSVRELNQHL RGLTKEEVTR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Mafk Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MAFK (Transcription Factor MafK (MAFK))
- Background
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Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor.
Alias Symbols: AW061068, NF-E2, Nfe2u
Protein Interaction Partner: Bach1,Bach2,Nfe2,Nfe2l2,Nfe2l2,Nr4a3
Protein Size: 156 - Molecular Weight
- 17 kDa
- Gene ID
- 17135
- NCBI Accession
- NM_010757, NP_034887
- UniProt
- Q61827
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