Vasodilator-Stimulated phosphoprotein (VASP) (Middle Region) Peptide
VASP
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all VASP products
- VASP (Vasodilator-Stimulated phosphoprotein (VASP))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- WSVPNGPSPE EVEQQKRQQP GPSEHIERRV SNAGGPPAPP AGGPPPPPGP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-VASP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- VASP (Vasodilator-Stimulated phosphoprotein (VASP))
- Background
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Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
Alias Symbols: -
Protein Interaction Partner: APBB1IP,TES,ABI1,ACTA1,ACTG1,APBB1,APBB1IP,DMRTB1,ERMAP,FYB,GSN,LPP,NOL3,PFN1,PFN2,PLSCR1,PRKACA,PRKG1,SPTA1,TES,TRIM9,VASP,VCL,WAS,WWP2,XPO6,ZYX,APBB1,DMRTB1,DNMBP,FYB,NOL3,PFN1,PFN2,PLSCR1,PRPF40A,RAPH1,TES,TRIM9,VASP,VCL,WAS,WWP2,XPO6,ZYX
Protein Size: 380 - Molecular Weight
- 42 kDa
- Gene ID
- 7408
- NCBI Accession
- NM_003370, NP_003361
- UniProt
- P50552
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