Protein Summary

This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.

Alternative names and synonyms associated with PPP2R1B

• protein phosphatase 2, regulatory subunit A, beta (Ppp2r1b) antibody
• protein phosphatase 2 scaffold subunit Abeta (PPP2R1B) antibody
• protein phosphatase 2 scaffold subunit A beta (Ppp2r1b) antibody
• protein phosphatase 2 regulatory subunit A, beta S homeolog (ppp2r1b.S) antibody

• 2410091N08Rik antibody
• AI790395 antibody
• PP2A-Abeta antibody
• PR65B antibody

Protein level used designations for PPP2R1B

PP2A subunit A isoform PR65-beta , PP2A subunit A isoform R1-beta , serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform , PP2A, subunit A, PR65-beta isoform , PP2A, subunit A, R1-beta isoform , protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform , protein phosphatase 2, structural/regulatory subunit A, beta , protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform , Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform , protein phosphatase 2A 65 kDa regulatory subunit, beta isoform , phosphorylase phosphatase