anti-Coagulation Factor III (thromboplastin, Tissue Factor) Antibodies

Protein Summary

This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with Coagulation Factor III (thromboplastin, Tissue Factor) (F3)

• coagulation factor III, tissue factor (F3) antibody
• coagulation factor IIIa (f3a) antibody
• coagulation factor III (F3) antibody
• tissue factor (tf) antibody
• coagulation factor IIIb (f3b) antibody
• Show all gene names
• coagulation factor III (thromboplastin, tissue factor) S homeolog (f3.S) antibody

• AA409063 antibody
• CD142 antibody
• Cf-3 antibody
• Cf3 antibody
• f3 antibody
• Show all synonym aliases
• tf antibody
• TFA antibody
• zgc:112151 antibody

Protein level used designations for F3

tissue factor , TFa , coagulation factor III , thromboplastin , TF , coagulation factor 3 , brain tissue factor , TFb , coagulation factor IIIb , coagulation factor III (thromboplastin, tissue factor) S homeolog