Browse our PEPCK Proteins (PEPCK)

Full name:: phosphoenolpyruvate Carboxykinase 2 (Mitochondrial) Proteins (PEPCK)

On www.antibodies-online.com are 5 phosphoenolpyruvate Carboxykinase 2 (Mitochondrial) (PEPCK) Proteins from 4 different suppliers available. Additionally we are shipping PEPCK Antibodies (92) and PEPCK Kits (19) and many more products for this protein. A total of 123 PEPCK products are currently listed.

Synonyms:: 1810010O14Rik, 9130022B02Rik, id:ibd5157, pck, pck2, pck2.S, PEPCK, PEPCK-M, PEPCK2, zgc:77867

list all proteins	Gene Name	GeneID	UniProt
	PEPCK	5106	Q16822
	PEPCK	74551	Q8BH04
Rat PEPCK	PEPCK	361042
Show all synonyms

PEPCK Proteins (PEPCK) by Origin

Select your origin of interest

Relevant Pathways for PEPCK Proteins

More product categories related to PEPCK Protein

Top referenced PEPCK Proteins

Human PEPCK Protein expressed in Wheat germ - ABIN1314318 : Kanno, Watanabe, Takahashi, Abe, Ohira: Anti-phosphoenolpyruvate carboxykinase 2 antibody in patients with autoimmune hepatitis. in Hepatology research : the official journal of the Japan Society of Hepatology 2014 (PubMed)

More Proteins for PEPCK Interaction Partners

Human phosphoenolpyruvate Carboxykinase 2 (Mitochondrial) (PEPCK) interaction partners

Our study indicates that the T allele of the rs4982856 single-nucleotide polymorphisms in the PCK2 gene may be a risk factor for glucose intolerance after kidney transplantation
Downregulation of PCK2 remodels tricarboxylic acid cycle in tumor-repopulating cells of melanoma
ApoA-IV (show APOA4 Proteins) colocalizes with NR4A1 (show NR4A1 Proteins), which suppresses G6Pase (show G6PC Proteins) and PEPCK gene expression at the transcriptional level, reducing hepatic glucose output and lowering blood glucose.
Results indicate that PEPCK promotes tumor growth by increasing glucose and glutamine metabolism, increases anabolic metabolism and promotes mTORC1 activity.
Mitochondrial PCK2 regulates metabolic adaptation and enables glucose-independent tumor growth in various neoplasms.
When autophagy was blocked, the level of glucose-6-phosphatase (G6Pase (show G6PC Proteins)) and phosphoenolpyruvate carboxykinase (PEPCK) was reduced in HepG2 cells and not in Hep3B cells.
PEPCK activity was elevated threefold in lung cancer samples over normal lungs and its activation mediates an adaptive response to glucose depletion in lung cancer.
Amino acid limitation and ER stress inducers, conditions that activate the amino acid response (AAR) and the unfolded protein response (UPR), stimulate PCK2 gene transcription in tumor cell lines.
Expression of phosphoenolpyruvate carboxykinase linked to chemoradiation susceptibility of human colon cancer cells.
expression of HCV nonstructural component NS5A in Huh7 or primary hepatocytes stimulated PEPCK gene expression and glucose output in HepG2 cells.

Mouse (Murine) phosphoenolpyruvate Carboxykinase 2 (Mitochondrial) (PEPCK) interaction partners

Downregulation of PCK2 remodels tricarboxylic acid cycle in tumor-repopulating cells of melanoma
Lactate maintains/induces populations of postnatal neuronal progenitors/neural stem cells in a PEPCK-M-dependent manner
Amino acid limitation and ER stress inducers, conditions that activate the amino acid response (AAR) and the unfolded protein response (UPR), stimulate PCK2 gene transcription in tumor cell lines.
PEPCK-M expression partially rescued defects in lipid metabolism, gluconeogenesis and TCA cycle function impaired by PEPCK-C deletion, while approximately 10% re-expression of PEPCK-C normalized most parameters.
Data show that PEPCK-M message and protein were detected in islets.

Cow (Bovine) phosphoenolpyruvate Carboxykinase 2 (Mitochondrial) (PEPCK) interaction partners

Transition to lactation does not alter expression of the mitochondrial form of PEPCK.

Pig (Porcine) phosphoenolpyruvate Carboxykinase 2 (Mitochondrial) (PEPCK) interaction partners

Concurrent binding and modifications of AUF1 (show HNRNPD Proteins) and HuR (show ELAVL1 Proteins) mediate the pH-responsive stabilization of phosphoenolpyruvate carboxykinase mRNA in kidney cells.

PEPCK Protein Profile

Protein Summary

This gene encodes a member of the phosphoenolpyruvate carboxykinase (GTP) family. The protein is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of GTP. A cytosolic form encoded by a different gene has also been characterized and is the key enzyme of gluconeogenesis in the liver. The encoded protein may serve a similar function, although it is constitutively expressed and not modulated by hormones such as glucagon and insulin that regulate the cytosolic form. Alternatively spliced transcript variants have been described.

Alternative names and synonyms associated with PEPCK

phosphoenolpyruvate carboxykinase 2, mitochondrial (PCK2)
phosphoenolpyruvate carboxykinase 2 (mitochondrial) (Pck2)
phosphoenolpyruvate carboxykinase 2 (mitochondrial) (pck2)
phosphoenolpyruvate carboxykinase 2, mitochondrial (Pck2)
phosphoenolpyruvate carboxykinase 2 (mitochondrial) L homeolog (pck2.L)

1810010O14Rik protein
9130022B02Rik protein
id:ibd5157 protein
pck protein
pck2 protein
pck2.S protein
PEPCK protein
PEPCK-M protein
PEPCK2 protein
zgc:77867 protein

Protein level used designations for PEPCK

PEP carboxykinase , phosphoenolpyruvate carboxykinase [GTP], mitochondrial , phosphoenolpyruvate carboxylase , phosphopyruvate carboxylase , mitochondrial phosphoenolpyruvate carboxykinase 2 , phosphoenolpyruvate carboxykinase 2 (mitochondrial) L homeolog , phosphoenolpyruvate carboxykinase 2 (mitochondrial) S homeolog

GENE ID	SPECIES
5106	Homo sapiens
74551	Mus musculus
282856	Bos taurus
361042	Rattus norvegicus
396457	Gallus gallus
406473	Danio rerio
452807	Pan troglodytes
480255	Canis lupus familiaris
100054903	Equus caballus
403165	Sus scrofa
100715252	Cavia porcellus
399424	Xenopus laevis

Selected quality suppliers for PEPCK Proteins (PEPCK)

Did you look for something else?

Phone:	+1 877 302 8632
Fax:	+1 888 205 9894 (Toll-free)
E-Mail:	orders@antibodies-online.com

Show all phosphoenolpyruvate Carboxykinase 2 (Mitochondrial) Proteins (PEPCK) with Pubmed References