Browse our TRAF3IP2 Proteins (TRAF3IP2)

This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.

• TRAF3 interacting protein 2 (TRAF3IP2)
• TRAF3 interacting protein 2 (Traf3ip2)
• Traf3 interacting protein 2 (Traf3ip2)
• adapter protein CIKS (LOC100473939)
• TRAF3 interacting protein 2 L homeolog (traf3ip3.L)
• Show all gene names
• TRAF3 interacting protein 2 (traf3ip3)

• Act1 protein
• AI429613 protein
• C6orf2 protein
• C6ORF4 protein
• C6orf5 protein
• Show all synonym aliases
• C6orf6 protein
• CIKS protein
• MGC134034 protein
• PSORS13 protein
• RGD1304768 protein
• t3jam protein
• TRAF3IP2 protein

NFkB-activating protein ACT1 , adapter protein CIKS , connection to IKK and SAPK/JNK , nuclear factor NF-kappa-B activator 1 , TRAF3 interacting protein 2 , adapter protein CIKS-like