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Human Polyclonal CDC23 Primary Antibody for ICC, IF - ABIN4296891
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
cell division cycle protein 23
, cell division cycle protein 23 homolog
, cell division cycle 23 homolog (S. cerevisiae)
, CDC23 (cell division cycle 23, yeast, homolog)
, Cell division cycle protein 23 homolog
, cell division cycle protein 23 homolog-like
, anaphase-promoting complex subunit 8
, cyclosome subunit 8
, anaphase promoting complex subunit 8
, cell division cycle 23 homolog