FTH1 Protein (AA 2-183, full length) (GST tag)

Catalog No. ABIN1047000

Product Details

Target: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Protein Type: Recombinant

Protein Characteristics: AA 2-183, full length

Reactivity: Please inquire

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This FTH1 protein is labelled with GST tag.

Application: ELISA

Sequence: TTASTSQVRQ NYHQDSEAAI NRQINLELYA SYVYLSMSYY FDRDDVALKN FAKYFLHQSH EEREHAEKLM KLQNQRGGRI FLQDIKKPDC DDWESGLNAM ECALHLEKNV NQSLLELHKL ATDKNDPHLC DFIETHYLNE QVKAIKELGD HVTNLRKMGA PESGLAEYLF DKHTLGDSDN ES

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C for extended storage, conserve at -20 °C or -80 °C

References

Chou, Gatti, Fuller, Concannon, Wong, Chada, Davis, Salser: "Structure and expression of ferritin genes in a human promyelocytic cell line that differentiates in vitro." in: Molecular and cellular biology, Vol. 6, Issue 2, pp. 566-73, (1987) (PubMed).

Boyd, Vecoli, Belcher, Jain, Drysdale: "Structural and functional relationships of human ferritin H and L chains deduced from cDNA clones." in: The Journal of biological chemistry, Vol. 260, Issue 21, pp. 11755-61, (1985) (PubMed).

Costanzo, Santoro, Colantuoni, Bensi, Raugei, Romano, Cortese: "Cloning and sequencing of a full length cDNA coding for a human apoferritin H chain: evidence for a multigene family." in: The EMBO journal, Vol. 3, Issue 1, pp. 23-7, (1984) (PubMed).

Target Details

Target: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Alternative Name: Ferritin heavy chain protein (FTH1 Products)

Synonyms: FHC Protein, FTH Protein, FTHL6 Protein, PIG15 Protein, PLIF Protein, apoferritin Protein, ferritin Protein, fhc Protein, fth Protein, fth1 Protein, fthl6 Protein, ftn-2 Protein, pig15 Protein, plif Protein, fth1b Protein, Fth Protein, HFt Protein, MFH Protein, fb06g09 Protein, hm:zeh1145 Protein, wu:fb06g09 Protein, wu:fq18c10 Protein, zeh1145 Protein, ferritin heavy chain 1 Protein, ferritin, heavy polypeptide 1 L homeolog Protein, ferritin, heavy polypeptide 1 S homeolog Protein, ferritin heavy polypeptide 1 Protein, ferritin, heavy polypeptide 1a Protein, ferritin Protein, ferritin, heavy polypeptide 1 Protein, tudor domain containing 9 Protein, ferritin, heavy polypeptide 1 a Protein, FTH1 Protein, fth1.L Protein, fth1.S Protein, Fth1 Protein, fth1a Protein, EAMY_RS19690 Protein, fth1 Protein, TDRD9 Protein

Background: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney

Molecular Weight: 48.5 kD

UniProt: P25800

Pathways: Transition Metal Ion Homeostasis