FTH1 Protein
Quick Overview for FTH1 Protein (ABIN7318467)
Target
See all FTH1 ProteinsProtein Type
Origin
Source
Purity
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Purpose
- Recombinant Human FTH Protein
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Sequence
- Met 1-Ser183
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Characteristics
- Recombinant Human Ferritin heavy chain is produced by our E.coli expression system and the target gene encoding Met1-Ser183 is expressed.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Ferritin, Heavy Polypeptide 1 (FTH1) (AA 1-182) protein (His tag)
custom-made FTH1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Ferritin, Heavy Polypeptide 1 (FTH1) (AA 1-183) protein (His tag)custom-made FTH1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Ferritin, Heavy Polypeptide 1 (FTH1) (AA 1-183) protein (GST tag)FTH1 Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
Ferritin, Heavy Polypeptide 1 (FTH1) (AA 2-183), (full length) protein (GST tag)FTH1 Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
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Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))
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Alternative Name
- FTH
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Background
- Cell proliferation-inducing gene 15 protein,FHC,FTH,FTH1,FTHL6,Ferritin H subunit,Ferritin heavy chain,HFE5,PIG15,Ferritin heavy polypeptide 1(FTH1), is a ubiquitous intracellular protein which stores iron in a soluble, non-toxic, readily available form. FTH1 has ferroxidase activity and is important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Ferritin is composed of 24 subunits of the light and heavy ferritin chains. It plays a role in delivery of iron to cells and mediates iron uptake in capsule cells of the developing kidney. Variation of ferritin subunit composition may affect iron absorption and release in different tissues. Deficiency of ferritin proteins may cause several neurodegenerative diseases. Almost all living organisms can produce this protein, including algae, bacteria, higher plants, and animals.
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Molecular Weight
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Calculated MW: 21.2 kDa
Observed MW: 20 kDa
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Gene ID
- 2495
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UniProt
- P02794
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Pathways
- Transition Metal Ion Homeostasis
Target
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