Slc25a1 Protein (AA 47-87, partial) (GST tag)

Catalog No. ABIN1047776

Product Details

Target: Slc25a1 (Solute Carrier Family 25 (Mitochondrial Carrier, Citrate Transporter), Member 1 (Slc25a1))

Protein Type: Recombinant

Protein Characteristics: AA 47-87, partial

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This Slc25a1 protein is labelled with GST tag.

Application: ELISA

Sequence: EYVKTQLQLD ERSHPPRYRG IGDCVRQTVR SHGVLGLYRG L

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C for extended storage, conserve at -20 °C or -80 °C

References

Heisterkamp, Mulder, Langeveld, ten Hoeve, Wang, Roe, Groffen: "Localization of the human mitochondrial citrate transporter protein gene to chromosome 22Q11 in the DiGeorge syndrome critical region." in: Genomics, Vol. 29, Issue 2, pp. 451-6, (1996) (PubMed).

Target Details

Target: Slc25a1 (Solute Carrier Family 25 (Mitochondrial Carrier, Citrate Transporter), Member 1 (Slc25a1))

Alternative Name: Tricarboxylate transport protein, mitochondrial protein (Slc25a1 Products)

Background: Involved in citrate-H+/malate exchange. Important for the bioenergetics of hepatic cells as it provides a carbon source for fatty acid and sterol biosyntheses, and NAD+ for the glycolytic pathway.

Molecular Weight: 32.2 kD

UniProt: P53007