Caspase Recruitment Domain-Containing Protein 18 (ICEBERG) (CARD18) protein (His tag)

Details for Product No. ABIN1098230
Protein Name
Origin
Human
5
Source
Escherichia coli (E. coli)
2
2
1
Protein Type
Recombinant
Purification tag / Conjugate
His tag
Application
SDS-PAGE (SDS)
Options
Purification purified by chromatography
Purity > 95 % by SDS - PAGE
Protein Name
Background Caspase recruitment domain-containing protein 18, also known as CARD18, is a member of the death-domain-fold superfamily that is induced by proinflammatory stimuli. It consists essentially only of a CARD, inhibits generation of IL-1b by interacting with caspase-1 and preventing association with RIP 2. The association of CARD18 with caspase-1 is facilitated by the charge-charge interactions between the prodomain of caspase-1 and the surface charge of CARD18. Recombinant human CARD18 proetin, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Molecular Weight 12.3 kDa (110aa), confirmed by MALDI-TOF
NCBI Accession NP_067546
Comment

Synonyms: Caspase recruitment domain-containing protein 18, ICEBERG, pseudo-ICE, UNQ5804

Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/ml (determined by Bradford assay)
Buffer 20 mM Tris-HCl buffer (pH 8.0) containing 1 MM DTT,10% glycerol, 0.1 M NaCl
Storage 4 °C
Storage Comment Avoid repeated freezing and thawing cycles.
Supplier Images
Image no. 1 for Caspase Recruitment Domain-Containing Protein 18 (ICEBERG) (CARD18) protein (His tag) (ABIN1098230) Caspase Recruitment Domain-Containing Protein 18 (ICEBERG) (CARD18) protein (His tag)