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ARFIP2 Protein (His tag)

ARFIP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN1098383
  • Target See all ARFIP2 Proteins
    ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))
    Protein Type
    Recombinant
    Origin
    • 6
    • 2
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This ARFIP2 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Purification
    purified by chromatography
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product ARFIP2 Protein
  • Comment

    Synonyms: Arfaptin 2, POR1

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 40% glycerol,1 MM DTT
    Storage
    4 °C
    Storage Comment
    Avoid repeated freezing and thawing cycles.
  • Target
    ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))
    Alternative Name
    ARFIP2 (ARFIP2 Products)
    Background
    Arfaptin 2, also known as ARFIP2, is a Rac1 binding protein necessary for Rac-mediated actin polymerization and the subsequent formation of membrane ruffles and lamellipodia. ARFIP2 has also been shown to interact with the ADP ribosylation factor ARF6, a GTPase that associates with the plasma membrane and intracellular endosome vesicles, in a GTP dependent manner. Arfaptin 2 also regulates the aggregation of mutant Huntingtin protein by possibly impairing proteasome function. Expression of ARFIP2 was shown to be increased at sites of neurodegeneration. Recombinant human ARFIP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molecular Weight
    40.2 kDa (364aa), confirmed by MALDI-TOF
    NCBI Accession
    NP_036534
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