DLK1 Protein (AA 1-303) (DYKDDDDK Tag)
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- Target See all DLK1 Proteins
- DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-303
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DLK1 protein is labelled with DYKDDDDK Tag.
- Application
- SDS-PAGE (SDS)
- Purpose
- DLK1 (human) (rec.)
- Cross-Reactivity
- Human
- Characteristics
- Signal peptide and extracellular domain of human DLK1 (aa 1-303) are fused at the C-terminus to a FLAG®-tag.
- Purity
- >90 % (SDS-PAGE)
- Endotoxin Level
- <0.1EU/μg purified protein (LAL test).
- Top Product
- Discover our top product DLK1 Protein
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delta-Like 1 Homolog (Drosophila) (DLK1) (AA 24-303) protein (His tag)
DLK1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
delta-Like 1 Homolog (Drosophila) (DLK1) (AA 24-305) protein (His tag)DLK1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
delta-Like 1 Homolog (Drosophila) (DLK1) (AA 24-303) protein (Fc Tag)DLK1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
delta-Like 1 Homolog (Drosophila) (DLK1) (AA 24-306) protein (His tag)DLK1 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
delta-Like 1 Homolog (Drosophila) (DLK1) (AA 24-303) protein (His tag)DLK1 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95 % by SDS - PAGE SDS
delta-Like 1 Homolog (Drosophila) (DLK1) (AA 25-383) protein (GST tag)DLK1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Contains PBS.
- Handling Advice
- After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. PBS containing at least 0.1 % BSA should be used for further dilutions.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
- Expiry Date
- 6 months
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- Target
- DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
- Alternative Name
- DLK1 (DLK1 Products)
- Background
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Protein Delta Homolog 1, Fetal Antigen 1, Preadipocyte Factor 1, Pref-1, FA1
The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1, Preadipocyte factor 1, Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.
- Molecular Weight
- ~40kDa (SDS-PAGE)
- UniProt
- P80370
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