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Annexin V Protein (GST tag)

ANXA5 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % (SDS-PAGE) SDS
Catalog No. ABIN1344454
  • Target See all Annexin V (ANXA5) Proteins
    Annexin V (ANXA5) (Annexin A5 (ANXA5))
    Protein Type
    Recombinant
    Origin
    • 15
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 24
    • 8
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Annexin V protein is labelled with GST tag.
    Application
    SDS-PAGE (SDS)
    Specificity
    Binds to phosphatidylserine (PS).
    Cross-Reactivity
    Human
    Characteristics
    Recombinant human annexin V fused to a GST-tag.
    Purity
    >95 % (SDS-PAGE)
    Top Product
    Discover our top product ANXA5 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with 100 μL sterile water.
    Concentration
    Lot specific
    Buffer
    Lyophilized. In PBS, pH 7.4.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C. Reconstituted solutions can be kept at 4°C under sterile conditions for one week or should be frozen in aliquots at -20°C.
    Expiry Date
    12 months
  • Morizono, Chen: "Role of phosphatidylserine receptors in enveloped virus infection." in: Journal of virology, Vol. 88, Issue 8, pp. 4275-90, (2014) (PubMed).

  • Target
    Annexin V (ANXA5) (Annexin A5 (ANXA5))
    Alternative Name
    Annexin V (ANXA5 Products)
    Synonyms
    anx Protein, anx5 Protein, ANX V Protein, anxa5 Protein, cb989 Protein, wu:fa98f06 Protein, wu:fj10f10 Protein, MGC89158 Protein, ANX5 Protein, ENX2 Protein, PP4 Protein, RPRGL3 Protein, Anx5 Protein, R74653 Protein, LC5 Protein, enx2 Protein, annexin A5 Protein, annexin A5b Protein, Annexin A5 Protein, annexin A5 L homeolog Protein, ANXA5 Protein, anxa5b Protein, anxa5 Protein, Anxa5 Protein, anxa5.L Protein
    Background
    Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e.g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.
    Molecular Weight
    ~52kDa (SDS-PAGE)
    UniProt
    P08758
    Pathways
    Apoptosis
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