phosphoglycerate Dehydrogenase (PHGDH) (AA 2-251), (partial) protein (GST tag)

Details for Product No. ABIN1608043
Protein Name
Protein Characteristics
AA 2-251, partial
3
2
1
Origin
Human
8
1
1
Source
Escherichia coli (E. coli)
2
2
2
2
1
1
Protein Type
Recombinant
Purification tag / Conjugate
This PHGDH protein is labelled with GST tag.
Application
ELISA
Options
Sequence AFANLRKVLI SDSLDPCCRK ILQDGGLQVV EKQNLSKEEL IAELQDCEGL IVRSATKVTA DVINAAEKLQ VVGRAGTGVD NVDLEAATRK GILVMNTPNG NSLSAAELTC GMIMCLARQI PQATASMKDG KWERKKFMGT ELNGKTLGIL GLGRIGREVA TRMQSFGMKT IGYDPIISPE VSASFGVQQL PLEEIWPLCD FITVHTPLLP STTGLLNDNT FAQCKKGVRV VNCARGGIVD EGALLRALQS
Characteristics Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
Purity 95 %
Protein Name
Background Defects in PHGDH are the cause of phosphoglycerate dehydrogenase deficiency (PHGDH deficiency) [MIM:601815]. It is characterized by congenital microcephaly, psychomotor retardation, and seizures.
Molecular Weight 54.2 kD
UniProt O43175
Pathways Metabolism of Steroid Hormones and Vitamin D
Comment

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.
Restrictions For Research Use only
Format Lyophilized
Concentration 0.2-2 mg/mL
Buffer Tris-based buffer, 50 % glycerol
Handling Advice Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
Storage -20 °C
Storage Comment Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
Supplier Images
Image no. 1 for phosphoglycerate Dehydrogenase (PHGDH) (AA 2-251), (partial) protein (GST tag) (ABIN1608043) phosphoglycerate Dehydrogenase (PHGDH) (AA 2-251), (partial) protein (GST tag)