CYP21A2 Protein (AA 1-492) (His tag)

Catalog No. ABIN1622645

Product Details

Target: CYP21A2 (Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2))

Protein Type: Recombinant

Protein Characteristics: AA 1-492

Origin: Cat

Source: Yeast

Purification tag / Conjugate: This CYP21A2 protein is labelled with His tag.

Application: ELISA

Sequence: MLLLGLLLLT ALAGARLLWN KWKYRSLHLP PLAPGFLHLL QPDLPIYLLG LTQKLGPVYR LRLGLQDVVV LNSKRTIEEA LIRRWVDFAG RPQMPSYKLV SQHYQDLSLG DYSLLWKAHK KLTRSALLLG IRNSMEPLVE QLTQEFCERM RAQAGTPVAI QKEFSFLTCS VICCLTFGDK EDTLVHAFHD CVEDLMKSWE HWSIQVLDIV PFLRFFPNPG LRRLKQALEN RDRIVEKQLR QHKDSMVAGQ WRDMTDYMLQ GMGKPKVEKG HGRLLEGHVH MSVVDLFIGG TETTATTLSW AVAFLLHHPE IQQRLQEELD CELGPGASGS RVPLKDPSRL PLLTATIAEV LRLRPVVPLA LPHRTTRHSS ILGYDIPEGT VVIPNLQGAH LDDTVWEQPH EFRPDRFLVP GASPRVLAFG CGARVCLGEP LARLELFVVL ARLLHAFTLL PPTGPLPSLR PRSHCGINLT MQPFQVRLQP RGAVAPGPSQ HQ

Specificity: Felis catus (Cat) (Felis silvestris catus)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: CYP21A2 (Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2))

Alternative Name: Steroid 21-hydroxylase (CYP21) (CYP21A2 Products)

Synonyms: CA21H Protein, CAH1 Protein, CPS1 Protein, CYP21 Protein, CYP21B Protein, P450c21B Protein, 21-OH Protein, 21OH Protein, 21OHA Protein, 21OHB Protein, CYP21OH-A Protein, Cyp21 Protein, Cyp21-ps1 Protein, Cyp21B Protein, Cyp21a2-ps Protein, Cyp21a2ps Protein, Oh21-1 Protein, Oh21-2 Protein, CYP21A Protein, 21-OHase Protein, cytochrome P450 family 21 subfamily A member 2 Protein, cytochrome P450, family 21, subfamily a, polypeptide 1 Protein, cytochrome P450c21 Protein, cytochrome P450, family 21, subfamily A, polypepide 2 Protein, cytochrome P450, family 21, subfamily A, polypeptide 2 Protein, steroid 21-hydroxylase-like Protein, CYP21A2 Protein, Cyp21a1 Protein, LOC101094596 Protein

Background: Recommended name: Steroid 21-hydroxylase.
EC= 1.14.99.10.
Alternative name(s): 21-OHase Cytochrome P-450c21 Cytochrome P450 21 Cytochrome P450 XXI Cytochrome P450-C21

UniProt: Q2LA60

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process